Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.74 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | CA1 | P00915 | 2/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.71 |
| ▸ | CA7 | P43166 | 1/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.65 |
| ▸ | CNR1 | P21554 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.63 |
| ▸ | LTA4H | P09960 | 2/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4152553 | 0.91 | TRPV1 (0.78) | HPGDGAATRPV1CA2CA1 | |
| SCHEMBL4152627 | 0.91 | TRPV1 (0.78) | HPGDGAATRPV1CA2CA1 | |
| SCHEMBL6962982 | 0.90 | CA1 (0.69) | HPGDGAATRPV1CA2CA1 | |
| SCHEMBL8803541 | 0.90 | LTA4H (0.79) | HPGDGAATRPV1CA2CA1 | |
| SCHEMBL13332523 | 0.90 | EPHX2 (0.79) | HPGDGAATRPV1CA2CA1 | |
| SCHEMBL22664772 | 0.90 | CA1 (0.69) | HPGDGAATRPV1CA2CA1 | |
| SCHEMBL8156270 | 0.90 | HPGD (0.66) | HPGDGAATRPV1CA2CA1 | |
| SCHEMBL13209218 | 0.89 | GAA (1.00) | HPGDGAATRPV1ALDH1A1ATM | |
| SCHEMBL11706331 | 0.87 | TRPV1 (0.72) | HPGDGAATRPV1CA2CA1 | |
| SCHEMBL18891534 | 0.86 | HPGD (0.60) | HPGDGAATRPV1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187176-B | Method for preparing N-vinyl amide compound under catalysis of copper salt | 浙江工业大学 | 2022-11-25 | — | — | CN | claimed |
| CN-111187176-A | Method for preparing N-vinyl amide compound under catalysis of copper salt | 浙江工业大学 | 2020-05-22 | — | — | CN | claimed |
| CN-104419921-A | Water soluble silver protective agent, preparation method thereof, chemical silvering method and surface silver plated workpiece | BYD CO LTD | 2015-03-18 | — | — | CN | claimed |
| US-20090111874-A1 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES (RU) | 2009-04-30 | — | — | US | claimed |
| EP-1876169-A1 | PHENYL-CONTAINING N-ACYL AMINE AND AMINOACID DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, A PHARMACEUTICAL COMPOSITION AND THE USE THEREOF | Obschestvo S Ogranichennoi Otvetstennostiyu "Pharmenterprises" (RU) | 2008-01-09 | — | — | EP | claimed |
| EP-0754041-A4 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMA (US) | 1997-11-19 | — | — | EP | claimed |
| CN-1149252-A | Novel substituted tryptamines, phenylalkylamines and the like | INTERNEURON PHARMA (US) | 1997-05-07 | — | — | CN | claimed |
| EP-0754041-A1 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMACEUTICALS INCORPORATED (US) | 1997-01-22 | — | — | EP | claimed |
| WO-1995026723-A1 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMACEUTICALS, INC. (US) | 1995-10-12 | — | — | WO | claimed |
| CN-111187176-B | Method for preparing N-vinyl amide compound under catalysis of copper salt | 浙江工业大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-111187176-A | Method for preparing N-vinyl amide compound under catalysis of copper salt | 浙江工业大学 | 2020-05-22 | — | — | CN | disclosed |
| US-10377698-B2 | Diphenethylamine derivatives which are inter alia useful as analgesics and method for their production | UNIVERSITY OF INNSBRUCK (AT) | 2019-08-13 | — | — | US | disclosed |
| US-10377698-B2 | Diphenethylamine derivatives which are inter alia useful as analgesics and method for their production | UNIVERSITY OF INNSBRUCK (AT) | 2019-08-13 | — | — | US | disclosed |
| US-20180072654-A1 | Diphenethylamine Derivatives Which Are Inter Alia Useful As Analgesics And Method For Their Production | Spetea, Mariana, Dr. (AT) | 2018-03-15 | — | — | US | disclosed |
| EP-0754041-A1 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMACEUTICALS INCORPORATED (US) | 1997-01-22 | — | — | EP | disclosed |
| US-5580878-A | TREATING SLEEP DISORDERS | INTERNEURON PHARMACEUTICALS, INC. (US) | 1996-12-03 | — | — | US | disclosed |
| EP-0737204-A1 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995026723-A1 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMACEUTICALS, INC. (US) | 1995-10-12 | — | — | WO | disclosed |
| WO-1995015973-A1 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 1995-06-15 | — | — | WO | disclosed |
| US-5403851-A | Central nervous system and psychological disorders | INTERNEURON PHARMACEUTICALS, INC. (US) | 1995-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072654-A1 | Diphenethylamine Derivatives Which Are Inter Alia Useful As Analgesics And Method For Their Production | PNMT, OPRL1, OPRK1 | HPGD 394/4885GAA 312/4885TRPV1 16/4885 |
| US-10377698-B2 | Diphenethylamine derivatives which are inter alia useful as analgesics and method for their production | PNMT, OPRL1, OPRK1 | HPGD 475/4885GAA 385/4885TRPV1 22/4885 |
| US-20090111874-A1 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | PAH, MAOA, APEH | HPGD 230/4885GAA 63/4885TRPV1 2120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.