Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279171 | 1.00 | NPC1 (0.52) | NPC1GAARAB9AL3MBTL1CYP2C9 | |
| SCHEMBL3262328 | 0.80 | MEN1 (0.50) | NPC1RAB9AL3MBTL1CYP2C9CYP1A2 | |
| SCHEMBL3262329 | 0.80 | MEN1 (0.50) | NPC1RAB9AL3MBTL1CYP2C9CYP1A2 | |
| SCHEMBL8726001 | 0.79 | MEN1 (0.52) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL8726004 | 0.79 | MEN1 (0.52) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL31402609 | 0.77 | CETP (0.35) | CYP1A2CYP2C19ALDH1A1CYP2D6 | |
| SCHEMBL6682732 | 0.76 | ALDH1A1 (0.40) | NPC1GAARAB9AL3MBTL1CYP2C9 | |
| SCHEMBL6682728 | 0.76 | ALDH1A1 (0.40) | NPC1GAARAB9AL3MBTL1CYP2C9 | |
| SCHEMBL16700968 | 0.75 | ALPG (0.31) | — | |
| SCHEMBL17386515 | 0.74 | TLR8 (0.40) | NPC1GAARAB9AL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323682-A | BLEACHING CATALYSTS | CIBA GEIGY AG (CH) | 1982-04-06 | — | — | US | disclosed |
| US-4216320-A | Quinoxaline bleach catalysts | CIBA-GEIGY AG (CH) | 1980-08-05 | — | — | US | disclosed |
| US-4202698-A | DYE BLEACH CATALYSTS | CIBA-GEIGY AG (CH) | 1980-05-13 | — | — | US | disclosed |
| US-4145217-A | DYE BLEACH CATALYST | CIBA-GEIGY AG (CH) | 1979-03-20 | — | — | US | disclosed |