Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CASP1 | P29466 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CASP7 | P55210 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11282033 | 0.83 | ALPG (0.50) | AKR1B1ALPGKDM4EALDH1A1CASP1 | |
| SCHEMBL11270745 | 0.82 | ALPG (0.67) | AKR1B1ALPGKDM4EALDH1A1CASP1 | |
| SCHEMBL11270912 | 0.72 | AKR1B1 (0.51) | AKR1B1ALPGPTAFR | |
| SCHEMBL11277337 | 0.72 | ALPG (0.63) | AKR1B1ALPGKDM4EALDH1A1CASP1 | |
| SCHEMBL11275949 | 0.70 | ALPG (0.57) | AKR1B1ALPGKDM4EALDH1A1CASP1 | |
| SCHEMBL11009173 | 0.70 | ALPG (0.71) | AKR1B1ALPGKDM4EALDH1A1CASP1 | |
| SCHEMBL11005221 | 0.70 | AKR1B1 (0.68) | AKR1B1ALPGKDM4EALDH1A1CASP1 | |
| SCHEMBL9459767 | 0.69 | AKR1B1 (0.53) | AKR1B1ALPGKDM4EALDH1A1CASP1 | |
| SCHEMBL11270498 | 0.69 | ALPG (0.50) | AKR1B1ALPGKDM4EALDH1A1CASP1 | |
| SCHEMBL11245977 | 0.69 | AKR1B1 (0.71) | AKR1B1ALPGKDM4EALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348396-A | Substituted 11-oxo-11H-pyrido[2,1-b]quinazolines and method of inhibiting allergic reactions with them | HOFFMANN-LA ROCHE INC. (US) | 1982-09-07 | — | — | US | disclosed |