Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11278675 | 0.99 | ELANE (0.47) | ELANEPDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL11286104 | 0.88 | ELANE (0.48) | ELANEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11279710 | 0.80 | ELANE (0.47) | ELANEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11279425 | 0.77 | ELANE (0.47) | ELANEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11281180 | 0.77 | ALOX15 (0.60) | PDE4APDE4BPDE4CPDE4DALOX15 | |
| SCHEMBL11282406 | 0.77 | ALOX15 (0.60) | PDE4APDE4BPDE4CPDE4DALOX15 | |
| SCHEMBL11288199 | 0.76 | ALOX15 (0.44) | PDE4APDE4BPDE4CPDE4DALOX15 | |
| Hydrochloric Acid SCHEMBL11278676 | 0.76 | ELANE (0.46) | ELANEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11289625 | 0.74 | ALOX15 (0.46) | PDE4APDE4BPDE4CPDE4DALOX15 | |
| Hydrochloric Acid SCHEMBL11286111 | 0.74 | ELANE (0.49) | ELANEALDH1A1LMNACYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |