Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11278676 | 0.99 | ELANE (0.46) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| SCHEMBL11631275 | 0.86 | ALDH1A1 (0.49) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| Hydrochloric Acid SCHEMBL11286111 | 0.85 | ELANE (0.49) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| Hydrochloric Acid SCHEMBL11633271 | 0.85 | ADRB2 (0.50) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| SCHEMBL11282072 | 0.82 | ELANE (0.46) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| Perchlorate SCHEMBL11631444 | 0.81 | ALDH1A1 (0.44) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| SCHEMBL11281656 | 0.81 | ALOX15 (0.51) | ALDH1A1CYP3A4HIF1AALOX15KDM4E | |
| SCHEMBL11283973 | 0.78 | HIF1A (0.58) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Benzene SCHEMBL11284599 | 0.77 | TSHR (0.56) | ALDH1A1KDM4EGAATSHRRAB9A | |
| SCHEMBL11279715 | 0.77 | ELANE (0.48) | ELANEALDH1A1ADRB2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |