SCHEMBL11279674

SCHEMBL11279674

C/C(=C\CCC(O)CBr)CCC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FNTA P49354 7/20 0.39
FNTB P49356 7/20 0.39
KDM1A O60341 1/20 0.37
IMPDH2 P12268 6/20 0.37
MEN1 O00255 1/20 0.35
TRPA1 O75762 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
LMNA P02545 1/20 0.34
SLC15A2 Q16348 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11279676 1.00 FNTA (0.39) FNTAFNTBKDM1AIMPDH2MEN1
SCHEMBL11222037 0.83 FNTA (0.39) FNTAFNTBKDM1AIMPDH2MEN1
SCHEMBL11222034 0.83 FNTA (0.39) FNTAFNTBKDM1AIMPDH2MEN1
SCHEMBL8927123 0.75 FNTA (0.55) FNTAFNTBKDM1AIMPDH2MEN1
SCHEMBL23414914 0.74 KDM1A (0.41) FNTAFNTBKDM1AIMPDH2MEN1
SCHEMBL22555599 0.74 KDM1A (0.41) FNTAFNTBKDM1AIMPDH2MEN1
SCHEMBL17670590 0.73 LMNA (0.46) FNTAFNTBIMPDH2LMNASLC15A2
SCHEMBL11267758 0.73 ALOX15 (0.45) MEN1MAPTKMT2A
SCHEMBL17670591 0.73 LMNA (0.46) FNTAFNTBIMPDH2LMNASLC15A2
SCHEMBL10885753 0.73 FNTA (0.54) FNTAFNTBKDM1AIMPDH2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0054909-A2 9-Halo-8-hydroxy-4-methyl-4-nonenoic acids, derivatives thereof and a process for their preparation MITSUBISHI KASEI CORPORATION (JP) 1982-06-30 EP disclosed