Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.80 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.80 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.74 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.74 |
| ▸ | EGFR | P00533 | 11/20 | 0.67 |
| ▸ | LCK | P06239 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | RAF1 | P04049 | 1/20 | 0.61 |
| ▸ | BRAF | P15056 | 1/20 | 0.61 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.60 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.57 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3339302 | 0.89 | MAPT (1.00) | MAPTGRM1NCOA1NCOA3EGFR | |
| Hydrochloric Acid SCHEMBL7417527 | 0.87 | MAPT (0.97) | MAPTGRM1NCOA1NCOA3EGFR | |
| Hydrochloric Acid SCHEMBL29624330 | 0.87 | MAPT (0.97) | MAPTGRM1NCOA1NCOA3EGFR | |
| SCHEMBL27878333 | 0.87 | USP2 (0.65) | MAPTGRM1EGFRRAF1BRAF | |
| SCHEMBL8933760 | 0.85 | KDR (0.73) | MAPTGRM1EGFRHTTBRAF | |
| SCHEMBL15503743 | 0.85 | NCOA1 (1.00) | MAPTGRM1NCOA1NCOA3EGFR | |
| Hydrochloric Acid SCHEMBL8808497 | 0.84 | KDR (0.71) | MAPTGRM1EGFRNPC1HTT | |
| SCHEMBL28469600 | 0.84 | MAPT (0.80) | MAPTGRM1NCOA1NCOA3EGFR | |
| SCHEMBL9017048 | 0.81 | EGFR (0.70) | EGFRHTTRAF1BRAFERBB2 | |
| SCHEMBL2100465 | 0.81 | MAPT (0.84) | MAPTGRM1NCOA1NCOA3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57144266-A | — | — | None | — | — | JP | disclosed |
| JP-S57144266-A | 4-ANILINOQUINAZOLINE DERIVATIVE, ITS PREPARATION, AND ANALGESIC AND ANTIPHLOGISTIC AGENT CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT | SANKYO CO LTD | 1982-09-06 | — | — | JP | disclosed |