Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11272001 | 0.99 | P2RX7 (0.32) | P2RX7MAOBMAOACHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL11520149 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL11267503 | 0.68 | NPC1 (0.39) | MEN1ALDH1A1ALOX12KMT2AMAPK1 | |
| SCHEMBL28875333 | 0.66 | CHRNA7 (0.43) | MAOBMAOACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL11196354 | 0.59 | CHRNB2 (0.39) | MAOBMAOACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL19308891 | 0.59 | CHRNA7 (0.42) | MAOBMAOACHRNB2CHRNB4CHRNA3 | |
| Bromide SCHEMBL11623605 | 0.57 | NPSR1 (0.48) | MAOBMAOACHRNB2CHRNB4CHRNA3 | |
| Dazepinil SCHEMBL499286 | 0.57 | CHRNB2 (0.40) | MAOBMAOACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL11211464 | 0.57 | NPC1 (0.49) | MAOAKMT2A | |
| Dazepinil SCHEMBL121402 | 0.56 | CHRNB2 (0.39) | MAOBMAOACHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004173-B1 | 2,3-DIHYDROIMIDAZO (1,2-C) PYRIMIDINES, THEIR PREPARATION, FORMULATIONS CONTAINING THEM AND THEIR USE AS PHARMACEUTICALS | ELI LILLY AND COMPANY (US) | 1982-09-22 | — | — | EP | claimed |
| EP-0004173-A1 | 2,3-Dihydroimidazo (1,2-c) pyrimidines, their preparation, formulations containing them and their use as pharmaceuticals | ELI LILLY AND COMPANY (US) | 1979-09-19 | — | — | EP | claimed |
| US-4153695-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1979-05-08 | — | — | US | claimed |