Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 7/20 | 0.69 |
| ▸ | DBF4 | Q9UBU7 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GRM6 | O15303 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2690751 | 0.88 | CDC7 (0.68) | CDC7DBF4ALDH1A1HSD17B10GRM6 | |
| SCHEMBL29876744 | 0.88 | CDC7 (0.68) | CDC7DBF4ALDH1A1HSD17B10GRM6 | |
| SCHEMBL11163073 | 0.87 | ALDH1A1 (0.69) | CDC7DBF4ALDH1A1HSD17B10GRM6 | |
| SCHEMBL10268830 | 0.87 | CDC7 (0.67) | CDC7DBF4ALDH1A1HSD17B10GRM6 | |
| SCHEMBL8823140 | 0.85 | ALDH1A1 (0.70) | CDC7DBF4ALDH1A1HSD17B10GRM6 | |
| SCHEMBL8823115 | 0.85 | CDC7 (0.85) | CDC7DBF4ALDH1A1HSD17B10MAPT | |
| SCHEMBL5528106 | 0.85 | CDC7 (0.64) | CDC7DBF4ALDH1A1HSD17B10GRM6 | |
| SCHEMBL9750566 | 0.85 | CDC7 (0.51) | CDC7DBF4ALDH1A1HSD17B10NPC1 | |
| SCHEMBL3893108 | 0.84 | ALDH1A1 (0.71) | CDC7DBF4ALDH1A1HSD17B10HPGD | |
| SCHEMBL8823068 | 0.81 | CDC7 (0.59) | CDC7DBF4ALDH1A1HSD17B10GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336389-A | 2-Substituted-4-aryl-5-thiazolecarboxylic acids and their derivatives as safening agents | MONSANTO COMPANY (US) | 1982-06-22 | — | — | US | disclosed |