Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 7/20 | 0.68 |
| ▸ | DBF4 | Q9UBU7 | 7/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29876744 | 1.00 | CDC7 (0.68) | CDC7DBF4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11279731 | 0.88 | CDC7 (0.69) | CDC7DBF4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL19141292 | 0.87 | ALDH1A1 (0.53) | CDC7DBF4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8823140 | 0.86 | ALDH1A1 (0.70) | CDC7DBF4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11163073 | 0.86 | ALDH1A1 (0.69) | CDC7DBF4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10268830 | 0.86 | CDC7 (0.67) | CDC7DBF4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL954885 | 0.85 | CDC7 (0.69) | CDC7DBF4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL5528106 | 0.84 | CDC7 (0.64) | CDC7DBF4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8823115 | 0.84 | CDC7 (0.85) | CDC7DBF4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1919084 | 0.81 | ALDH1A1 (0.74) | CDC7DBF4ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | CDC7 1875/4885DBF4 3789/4885ALDH1A1 2042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.