SCHEMBL11279735

SCHEMBL11279735

CC(Oc1ccccc1Oc1ccccc1)C(N)=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.57
KMT2A Q03164 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.46
POLB P06746 1/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 3/20 0.45
MAPT P10636 1/20 0.45
BRD4 O60885 1/20 0.45
MAPK1 P28482 2/20 0.44
ALDH1A1 P00352 1/20 0.44
TSPO P30536 1/20 0.44
IRAK4 Q9NWZ3 1/20 0.44
PARP10 Q53GL7 1/20 0.43
CARM1 Q86X55 1/20 0.43
PRMT6 Q96LA8 1/20 0.43
KDM4E B2RXH2 1/20 0.43
TTR P02766 1/20 0.43
MEN1 O00255 1/20 0.43
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1538036 0.86 KMT2A (0.69) CTNNB1KMT2AL3MBTL1POLBLMNA
SCHEMBL28483915 0.85 KMT2A (0.67) CTNNB1KMT2AL3MBTL1POLBLMNA
SCHEMBL14783846 0.82 KMT2A (0.73) KMT2ASMN1; SMN2POLBLMNAHTT
SCHEMBL1328578 0.82 GAA (0.56) KMT2APOLBHTTPARP10KDM4E
SCHEMBL7077662 0.77 HPGD (0.54) KMT2AL3MBTL1HTTMAPTALDH1A1
SCHEMBL9731110 0.77 PDE4D (0.48) KMT2ASMN1; SMN2HTTALDH1A1IRAK4
SCHEMBL17748845 0.77 L3MBTL1 (0.47) CTNNB1KMT2AL3MBTL1POLBLMNA
SCHEMBL1685873 0.77 CTNNB1 (0.53) CTNNB1SMN1; SMN2L3MBTL1POLBLMNA
SCHEMBL9362429 0.76 KMT2A (0.59) KMT2AL3MBTL1POLBLMNATTR
SCHEMBL10535446 0.76 KMT2A (0.59) KMT2ASMN1; SMN2L3MBTL1POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0011802-B1 PHENOXY-PHENOXY-PROPIONIC ACID AMIDES, PROCESSES FOR THEIR PREPARATION, HERBICIDAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN CONTROLLING THE GROWTH OF WEEDS HOECHST AKTIENGESELLSCHAFT (DE) 1982-09-15 EP claimed