Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RHEB | Q15382 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11012886 | 0.85 | KMT2A (0.47) | ALDH1A1LMNATSHRKMT2AGAA | |
| SCHEMBL2962387 | 0.85 | KMT2A (0.47) | ALDH1A1LMNATSHRKMT2AGAA | |
| SCHEMBL24926216 | 0.83 | ALDH1A1 (0.50) | L3MBTL1HTTALDH1A1MAPK1LMNA | |
| SCHEMBL11028335 | 0.80 | L3MBTL1 (0.47) | L3MBTL1HTTALDH1A1MAPK1LMNA | |
| SCHEMBL11027708 | 0.80 | L3MBTL1 (0.47) | L3MBTL1HTTALDH1A1MAPK1LMNA | |
| SCHEMBL1538036 | 0.79 | KMT2A (0.69) | L3MBTL1HTTLMNAPOLBCTNNB1 | |
| SCHEMBL11210411 | 0.79 | L3MBTL1 (0.42) | L3MBTL1HTTALDH1A1MAPK1LMNA | |
| SCHEMBL21775576 | 0.79 | TSPO (0.43) | L3MBTL1HTTALDH1A1MAPK1LMNA | |
| SCHEMBL167127 | 0.78 | LMNA (0.52) | ALDH1A1LMNAPOLBLTA4HTSHR | |
| SCHEMBL15709 | 0.78 | LMNA (0.52) | ALDH1A1LMNAPOLBLTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218425-A1 | SILICONE COMPOUNDS | The Procter and Gamble Company (US) | 2017-09-20 | — | — | EP | disclosed |
| WO-2016077513-A1 | SILICONE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2016-05-19 | — | — | WO | disclosed |