SCHEMBL11279788

SCHEMBL11279788

CC1=CC(=O)C(C)=C(C2CCCCC2=O)C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 2/20 0.40
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
KMT2A Q03164 2/20 0.35
CES1 P23141 1/20 0.32
MAPT P10636 2/20 0.31
USP2 O75604 2/20 0.31
ALDH1A1 P00352 2/20 0.31
LMNA P02545 2/20 0.31
POLB P06746 1/20 0.31
MEN1 O00255 1/20 0.30
PLIN1 O60240 1/20 0.30
NR1I2 O75469 1/20 0.30
GSR P00390 1/20 0.30
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11279790 0.76 APLNR (0.40) KMT2AMAPTUSP2ALDH1A1LMNA
SCHEMBL5562560 0.63 CA1 (0.42) TLR4CA1CA2CA4KMT2A
SCHEMBL1138156 0.63 NPC1 (0.45) TLR4CA1CA2CA4KMT2A
SCHEMBL31495252 0.62 PTPN1 (0.46) NR1I2MAOAMAOBCDC25B
SCHEMBL8602853 0.62 CA1 (0.48) TLR4CA1CA2CA4KMT2A
SCHEMBL10446207 0.61 CYP2C19 (0.35) KMT2ACES1MAPTUSP2ALDH1A1
SCHEMBL9841825 0.61 CES1 (0.40) KMT2ACES1MAPTUSP2ALDH1A1
SCHEMBL31495256 0.61 PTPN1 (0.47) NR1I2MAOAMAOBCDC25B
SCHEMBL24815345 0.61 DDB1 (0.53) TLR4CA1CA2CA4KMT2A
SCHEMBL15874850 0.61 DDB1 (0.53) TLR4CA1CA2CA4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US claimed
US-4195998-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, QUINONE OR CARBAZIDE PHOTOREDUCTANT EASTMAN KODAK COMPANY (US) 1980-04-01 US claimed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4171221-A NONSILVER PHOTOGTAPHY EASTMAN KODAK COMPANY (US) 1979-10-16 US disclosed