SCHEMBL11279790

SCHEMBL11279790

CC1=CC(=O)C(C)=C(C2CCCCC2)C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APLNR P35414 2/20 0.40
PTPN1 P18031 2/20 0.38
CDC25B P30305 2/20 0.38
PTPRC P08575 1/20 0.38
PTPRF P10586 1/20 0.38
MAOA P21397 2/20 0.36
MAOB P27338 2/20 0.36
NR1I2 O75469 2/20 0.33
MEN1 O00255 2/20 0.33
USP2 O75604 2/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 2/20 0.33
BLM P54132 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4B O94953 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
ADRA1A P35348 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31495256 0.84 PTPN1 (0.47) APLNRPTPN1CDC25BPTPRCPTPRF
SCHEMBL31495252 0.81 PTPN1 (0.46) APLNRPTPN1CDC25BPTPRCPTPRF
SCHEMBL11279788 0.76 TLR4 (0.40) CDC25BMAOAMAOBNR1I2MEN1
SCHEMBL5587983 0.72 APLNR (0.38) APLNRPTPN1CDC25BPTPRCPTPRF
SCHEMBL19386509 0.72 PTPN1 (0.46) APLNRPTPN1CDC25BPTPRCPTPRF
SCHEMBL31495253 0.70 PTPN1 (0.46) APLNRPTPN1CDC25BPTPRCPTPRF
SCHEMBL17969772 0.70 PTPN1 (0.41) APLNRPTPN1CDC25BPTPRCPTPRF
SCHEMBL10782026 0.69 MAOA (0.52) APLNRPTPN1CDC25BPTPRCPTPRF
SCHEMBL30770696 0.69 MAOA (0.52) APLNRPTPN1CDC25BPTPRCPTPRF
SCHEMBL10446207 0.69 CYP2C19 (0.35) APLNRMEN1USP2ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US claimed
US-4195998-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, QUINONE OR CARBAZIDE PHOTOREDUCTANT EASTMAN KODAK COMPANY (US) 1980-04-01 US claimed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4171221-A NONSILVER PHOTOGTAPHY EASTMAN KODAK COMPANY (US) 1979-10-16 US disclosed