SCHEMBL1128007

SCHEMBL1128007

CC(C)(C)CC(C)(C)N(c1ccccc1)C(C)(C)CC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
POLB P06746 1/20 0.36
ESR1 P03372 1/20 0.34
TSHR P16473 2/20 0.33
HTT P42858 1/20 0.33
FAAH O00519 1/20 0.33
PHGDH O43175 1/20 0.33
MGLL Q99685 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GLA P06280 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29027385 0.91 MEN1 (0.36) MEN1KMT2ACYP3A4CYP2C9CYP2C19
SCHEMBL28675789 0.84 NPC1 (0.34) MEN1KMT2ACYP3A4CYP2C9CYP2C19
SCHEMBL44715 0.82 MEN1 (0.38) MEN1KMT2ACYP3A4CYP2C9CYP2C19
SCHEMBL26002570 0.82 MEN1 (0.38) MEN1KMT2ACYP3A4CYP2C9CYP2C19
SCHEMBL2324035 0.79 KMT2A (0.39) MEN1KMT2ACYP3A4CYP2C9CYP2C19
SCHEMBL28335588 0.78 SHBG (0.50) MEN1KMT2ACYP3A4ESR1TSHR
SCHEMBL9564926 0.76 ALDH1A1 (0.37) MEN1KMT2ACYP3A4CYP2C9CYP2C19
SCHEMBL2056786 0.72 MEN1 (0.40) MEN1KMT2ACYP3A4CYP2C9CYP2C19
SCHEMBL1128009 0.71 NPC1 (0.38) MEN1KMT2ACYP3A4CYP2C9CYP2C19
SCHEMBL28335589 0.71 ALDH1A1 (0.38) CYP3A4SMN1; SMN2POLBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111556864-B Compounds with stabilizing effect, preparation method and use thereof, compositions containing same and method for stabilizing organic components 弗劳恩霍弗应用研究促进协会 2022-07-08 CN disclosed
EP-2283021-A2 SWITCHABLE SPECIAL EFFECT SUBSTANCES BASF SE (DE) 2011-02-16 EP disclosed
WO-2009141288-A2 SWITCHABLE SPECIAL EFFECT SUBSTANCES BASF SE (DE) 2009-11-26 WO disclosed