Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | GBA1 | P04062 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291337 | 0.97 | KDM4E (0.56) | ALDH1A1KDM4EHTR2CHPGDGBA1 | |
| SCHEMBL11288329 | 0.87 | GBA1 (0.53) | ALDH1A1KDM4EHTR2CHPGDGBA1 | |
| SCHEMBL11103525 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KDM4EHTR2CHPGDTSHR | |
| SCHEMBL11281402 | 0.80 | HTR2C (0.67) | ALDH1A1KDM4EHTR2CHPGDGBA1 | |
| SCHEMBL11285357 | 0.80 | HTR2C (0.74) | ALDH1A1KDM4EHTR2CHPGDGBA1 | |
| SCHEMBL11284575 | 0.77 | HTR2C (0.67) | ALDH1A1KDM4EHTR2CHPGDGBA1 | |
| SCHEMBL11282863 | 0.77 | KDM4E (0.41) | ALDH1A1KDM4EHTR2CHPGDGBA1 | |
| SCHEMBL11396657 | 0.75 | HTR2C (0.60) | ALDH1A1KDM4EHTR2CHPGDGBA1 | |
| SCHEMBL11285567 | 0.74 | KDM4E (0.41) | ALDH1A1KDM4EHTR2CHPGDGBA1 | |
| SCHEMBL11288197 | 0.74 | HTR2A (0.51) | ALDH1A1KDM4EHTR2CHPGDGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |