Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278582 | 0.88 | HTR2C (0.58) | HTR2CKDM4EHPGDALDH1A1HTR2A | |
| SCHEMBL11284575 | 0.83 | HTR2C (0.67) | HTR2CKDM4EHPGDALDH1A1HTR2A | |
| SCHEMBL11291337 | 0.83 | KDM4E (0.56) | HTR2CKDM4EHPGDALDH1A1HTR2A | |
| SCHEMBL11281402 | 0.81 | HTR2C (0.67) | HTR2CKDM4EHPGDALDH1A1HTR2A | |
| SCHEMBL11280428 | 0.80 | ALDH1A1 (0.56) | HTR2CKDM4EHPGDALDH1A1HTR2A | |
| SCHEMBL11102181 | 0.79 | HTR2C (0.55) | HTR2CKDM4EHPGDALDH1A1HTR2A | |
| SCHEMBL1123586 | 0.76 | HTR2C (0.57) | HTR2CKDM4EHPGDALDH1A1HRH4 | |
| SCHEMBL605230 | 0.75 | HRH4 (0.57) | KDM4EALDH1A1HRH4HRH1HTR3E | |
| SCHEMBL11283262 | 0.75 | KMT2A (0.50) | HTR2CKDM4EHPGDALDH1A1HTR2A | |
| SCHEMBL11402503 | 0.74 | HTR2C (0.71) | HTR2CKDM4EHPGDALDH1A1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |