Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 18/20 | 1.00 |
| ▸ | ACE2 | Q9BYF1 | 11/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277937 | 0.93 | ACE (0.87) | ACEACE2 | |
| SCHEMBL11124339 | 0.89 | ACE (0.81) | ACEACE2LMNA | |
| SCHEMBL11124347 | 0.89 | ACE (0.81) | ACEACE2LMNA | |
| SCHEMBL11279585 | 0.89 | ACE (0.81) | ACEACE2LMNA | |
| SCHEMBL11268988 | 0.86 | ACE (1.00) | ACEACE2 | |
| SCHEMBL9791914 | 0.85 | ACE (0.75) | ACEACE2 | |
| SCHEMBL11120692 | 0.84 | ACE (0.82) | ACEACE2 | |
| SCHEMBL11120609 | 0.84 | ACE (0.82) | ACEACE2 | |
| SCHEMBL11122713 | 0.83 | ACE (1.00) | ACEACE2 | |
| SCHEMBL11122708 | 0.83 | ACE (1.00) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329473-A | HYPOTENSIVE AGENTS | SRI INTERNATIONAL | 1982-05-11 | — | — | US | disclosed |