Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279104 | 0.89 | ALDH1A1 (0.54) | HTTSMN1; SMN2MAPK1KMT2AMAPT | |
| SCHEMBL8191837 | 0.88 | KMT2A (0.52) | HTTSMN1; SMN2MAPK1KMT2AMAPT | |
| SCHEMBL10372081 | 0.88 | POLB (0.56) | HTTSMN1; SMN2MAPK1KMT2AMAPT | |
| SCHEMBL4051742 | 0.87 | ALDH1A1 (0.52) | MAPK1KMT2AMAPTHSD17B10PTGDR2 | |
| SCHEMBL5519643 | 0.86 | PTGDR2 (0.50) | HTTSMN1; SMN2MAPK1KMT2AMAPT | |
| SCHEMBL717699 | 0.86 | PTGDR2 (0.66) | HTTSMN1; SMN2MAPK1KMT2AMAPT | |
| SCHEMBL11263623 | 0.83 | KDM4E (0.53) | HTTSMN1; SMN2KMT2AMAPTPTGDR2 | |
| SCHEMBL13064183 | 0.83 | TSHR (0.64) | HTTMAPK1KMT2AMAPTHSD17B10 | |
| SCHEMBL5528125 | 0.83 | MAOB (0.60) | HTTSMN1; SMN2 | |
| SCHEMBL13755295 | 0.82 | MAPT (0.48) | HTTMAPK1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320061-A | ANTISPASMODIC AGENTS | KALI-CHEMIE PHARMA GMBH (DE) | 1982-03-16 | — | — | US | disclosed |
| US-4279905-A | GASTROINTESTINAL DISORDERS | KALI-CHEMIE PHARMA GMBH (DE) | 1981-07-21 | — | — | US | disclosed |