Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328151 | 0.92 | ALDH1A1 (0.57) | ALDH1A1CYP3A4HTTSMN1; SMN2KMT2A | |
| SCHEMBL11280545 | 0.89 | HTT (0.51) | ALDH1A1HPGDMAPK1CYP3A4HTT | |
| SCHEMBL7332880 | 0.89 | KMT2A (0.51) | ALDH1A1HPGDMAPK1CYP3A4HTT | |
| SCHEMBL10373684 | 0.88 | HTT (0.52) | ALDH1A1MAPK1HTTSMN1; SMN2KMT2A | |
| SCHEMBL2226744 | 0.87 | PTPN1 (0.52) | ALDH1A1HPGDMAPK1CYP3A4KMT2A | |
| SCHEMBL2225179 | 0.86 | LMNA (0.57) | ALDH1A1HPGDMAPK1CYP3A4SMN1; SMN2 | |
| SCHEMBL11274520 | 0.84 | GAA (0.54) | ALDH1A1CYP3A4HTTSMN1; SMN2KMT2A | |
| SCHEMBL11584099 | 0.84 | MEN1 (0.54) | ALDH1A1HPGDHTTSMN1; SMN2KMT2A | |
| SCHEMBL10651243 | 0.83 | HTT (0.48) | ALDH1A1CYP3A4HTTSMN1; SMN2KMT2A | |
| SCHEMBL11285247 | 0.83 | MAPT (0.55) | ALDH1A1HTTSMN1; SMN2MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320061-A | ANTISPASMODIC AGENTS | KALI-CHEMIE PHARMA GMBH (DE) | 1982-03-16 | — | — | US | disclosed |
| US-4279905-A | GASTROINTESTINAL DISORDERS | KALI-CHEMIE PHARMA GMBH (DE) | 1981-07-21 | — | — | US | disclosed |