Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277657 | 0.94 | MEN1 (0.46) | MEN1KMT2AMAPTL3MBTL1GAA | |
| SCHEMBL29108035 | 0.76 | HPGD (0.50) | MEN1KMT2AMAPTKDM4EHTT | |
| SCHEMBL30517180 | 0.76 | HPGD (0.50) | MEN1KMT2AMAPTKDM4EHTT | |
| SCHEMBL30517179 | 0.76 | HPGD (0.50) | MEN1KMT2AMAPTKDM4EHTT | |
| SCHEMBL780564 | 0.74 | PDGFRB (0.61) | MEN1KMT2AMAPTL3MBTL1GAA | |
| SCHEMBL16011599 | 0.73 | L3MBTL1 (0.50) | MEN1KMT2AMAPTL3MBTL1GAA | |
| SCHEMBL11283138 | 0.73 | HRH4 (0.48) | MEN1KMT2AMAPTKDM4EHTT | |
| SCHEMBL782190 | 0.73 | PKM (0.48) | MAPTL3MBTL1GAAKDM4EHPGD | |
| SCHEMBL31468188 | 0.72 | CYP3A4 (0.50) | MEN1KMT2AMAPTL3MBTL1HTT | |
| SCHEMBL29108036 | 0.72 | HRH4 (0.43) | MEN1KMT2AMAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018493-B1 | 2-SULFONYL-QUINOXALINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES | BAYER AG (DE) | 1982-12-01 | — | — | EP | disclosed |
| EP-0018493-A1 | 2-Sulfonyl-quinoxalines, processes for their preparation and their use as microbicides | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |