Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | SCN1A | P35498 | 3/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28947296 | 0.86 | LMNA (0.41) | LMNACYP2D6TSHRMAOAHTR3A | |
| SCHEMBL25412762 | 0.83 | LMNA (0.39) | LMNACYP2D6TSHRMAOAHTR3A | |
| SCHEMBL127393 | 0.83 | CHRM1 (0.46) | CYP1A2CYP3A4NPSR1BLMALDH1A1 | |
| SCHEMBL1060297 | 0.82 | LMNA (0.42) | LMNACYP2D6TSHRMAOAHTR3A | |
| Ammonia Solution, Strong SCHEMBL28164385 | 0.81 | CHRM1 (0.44) | CYP1A2CYP3A4NPSR1BLMALDH1A1 | |
| SCHEMBL28788342 | 0.81 | CHRM1 (0.44) | CYP1A2CYP3A4NPSR1BLMALDH1A1 | |
| SCHEMBL9066701 | 0.81 | MEN1 (0.42) | LMNACYP2D6TSHRMAOAHTR3A | |
| SCHEMBL25332851 | 0.80 | LMNA (0.42) | LMNACYP2D6TSHRMAOAHTR3A | |
| Hydrochloric Acid SCHEMBL28379284 | 0.78 | ESR1 (0.45) | LMNATSHRCYP3A4NPSR1BLM | |
| SCHEMBL28206941 | 0.78 | CHRM2 (0.40) | LMNACYP2D6TSHRMAOAHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2109441-B1 | POLYSILOXANE BLOCK COPOLYMERS | BASF SE (DE) | 2016-01-27 | — | — | EP | claimed |
| US-8378038-B2 | Polysiloxane block copolymers | BASF SE (DE) | 2013-02-19 | — | — | US | claimed |
| US-8273216-B2 | Process for the production of paper | AKZO NOBEL N.V. (NL) | 2012-09-25 | — | — | US | claimed |
| US-8148318-B2 | Home or fabric care compositions comprising certain dye-polymer complexes | BASF SE (DE) | 2012-04-03 | — | — | US | claimed |
| US-8147814-B2 | Personal care compositions comprising certain dye-polymer complexes | BASF SE (DE) | 2012-04-03 | — | — | US | claimed |
| US-20100303750-A1 | POLYSILOXANE BLOCK COPOLYMERS | KOROSKENYI BALINT | 2010-12-02 | — | — | US | claimed |
| US-7732525-B2 | Polymers for paper and paperboard coatings | CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) | 2010-06-08 | — | — | US | claimed |
| EP-2109441-A2 | POLYSILOXANE BLOCK COPOLYMERS | Ciba Holding Inc. (CH) | 2009-10-21 | — | — | EP | claimed |
| EP-2046932-A2 | COMPOSITION FOR IMPROVING WETTABILITY OF SURFACES | Ciba Holding Inc. (CH) | 2009-04-15 | — | — | EP | claimed |
| US-20080199418-A1 | Polysiloxane block copolymers | BASF SE (DE) | 2008-08-21 | — | — | US | claimed |
| WO-2008095822-A2 | POLYSILOXANE BLOCK COPOLYMERS | CIBA HOLDING INC. (CH) | 2008-08-14 | — | — | WO | claimed |
| US-20080033106-A1 | Composition for improving wettability of surfaces | CIBA SPECIALTY CHEMICALS CORP. | 2008-02-07 | — | — | US | claimed |
| WO-2008015138-A2 | COMPOSITION FOR IMPROVING WETTABILITY OF SURFACES | CIBA HOLDING INC. (CH) | 2008-02-07 | — | — | WO | claimed |
| EP-3116919-B1 | NEW POLYELECTROLYTIC POLYMERS, PROCESS FOR THEIR PREPARATION AND USES THEREOF | ITALMATCH CHEMICALS SPA (IT) | 2020-08-26 | — | — | EP | disclosed |
| CN-106536574-B | Polyelectrolyte polymers, Its Preparation Method And Use | 伊塔尔麦奇化学股份公司 | 2019-02-22 | — | — | CN | disclosed |
| US-9771437-B2 | Polyelectrolytic polymers, process for their preparation and uses thereof | ITALMATCH CHEMICALS S.P.A. (IT) | 2017-09-26 | — | — | US | disclosed |
| EP-0892819-A1 | OIL, WATER AND SOLVENT RESISTANT PAPER BY TREATMENT WITH FLUOROCHEMICAL COPOLYMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997039036-A1 | OIL, WATER AND SOLVENT RESISTANT PAPER BY TREATMENT WITH FLUOROCHEMICAL COPOLYMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-10-23 | — | — | WO | disclosed |
| US-5674961-A | SURFACE TREATMENT WITH PROTECTIVE COATING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| US-4354907-A | TERTIARY OR QUATERNARY SALTS OF AMINOALKYL ACRYLATES | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) | 1982-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100303750-A1 | POLYSILOXANE BLOCK COPOLYMERS | KRT18, PUF60, SCNN1B | LMNA 2096/4885CYP2D6 4277/4885TSHR 4325/4885 |
| US-20080199418-A1 | Polysiloxane block copolymers | KRT18, PUF60, SCNN1B | LMNA 2096/4885CYP2D6 4277/4885TSHR 4325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.