Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | SCN1A | P35498 | 3/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28947296 | 0.83 | LMNA (0.41) | MEN1POLBKMT2ALMNACYP2D6 | |
| SCHEMBL10764193 | 0.82 | TSHR (0.38) | POLBLMNACYP2D6TSHRALDH1A1 | |
| SCHEMBL25412762 | 0.81 | LMNA (0.39) | MEN1POLBKMT2ALMNACYP2D6 | |
| SCHEMBL1128073 | 0.81 | LMNA (0.39) | MEN1POLBKMT2ALMNACYP2D6 | |
| SCHEMBL1060297 | 0.80 | LMNA (0.42) | MEN1POLBKMT2ALMNACYP2D6 | |
| SCHEMBL8971295 | 0.79 | TSHR (0.50) | LMNACYP2D6TSHRCYP1A2CYP3A4 | |
| SCHEMBL7758552 | 0.78 | TSHR (0.44) | CYP2D6TSHRCYP2C19 | |
| SCHEMBL7758545 | 0.78 | TSHR (0.44) | CYP2D6TSHRCYP2C19 | |
| SCHEMBL6909255 | 0.78 | THRB (0.35) | CYP2D6TSHRALDH1A1CYP2C19 | |
| SCHEMBL2788636 | 0.78 | GAA (0.40) | MEN1KMT2ALMNACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465835-B1 | Anionic living polymers, their derivatives and composition comprising them | DAINIPPON INK & CHEMICALS (JP) | 1996-05-01 | — | — | EP | disclosed |