Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 8/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11403086 | 1.00 | MAPK1 (0.36) | MAPK1SMN1; SMN2ALDH1A1KDM4EGLA | |
| SCHEMBL8575692 | 0.90 | ALDH1A1 (0.43) | MAPK1SMN1; SMN2ALDH1A1KDM4EACHE | |
| SCHEMBL8575690 | 0.90 | ALDH1A1 (0.43) | MAPK1SMN1; SMN2ALDH1A1KDM4EACHE | |
| SCHEMBL11631150 | 0.89 | EPHX1 (0.47) | ALDH1A1ACHEEPHX1 | |
| SCHEMBL11631146 | 0.89 | EPHX1 (0.47) | ALDH1A1ACHEEPHX1 | |
| SCHEMBL11625997 | 0.88 | EPHX1 (0.50) | ACHEEPHX1 | |
| SCHEMBL11626000 | 0.88 | EPHX1 (0.50) | ACHEEPHX1 | |
| SCHEMBL858575 | 0.85 | TSHR (0.31) | — | |
| SCHEMBL18249819 | 0.85 | — | — | |
| SCHEMBL20579336 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4312873-A | FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1982-01-26 | — | — | US | disclosed |
| US-4299837-A | IN ANIMALS | MONTEDISON S.P.A. (IT) | 1981-11-10 | — | — | US | disclosed |
| US-4191764-A | FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1980-03-04 | — | — | US | disclosed |
| US-4139626-A | FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1979-02-13 | — | — | US | disclosed |
| EP-0000089-A1 | Imidazole-2-carbamates and process for their production and pharmaceutical compositions containing them. | SYNTEX (U.S.A.) INC. (US) | 1978-12-20 | — | — | EP | disclosed |
| US-4110463-A | IMIDAZOLE-2-CARBAMATES | SYNTEX (U.S.A.) INC. (US) | 1978-08-29 | — | — | US | disclosed |
| US-4086235-A | PESTICIDES, ANTHELMINTICS, ANTIFUNGAL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4080461-A | PESTICIDES, FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1978-03-21 | — | — | US | disclosed |
| US-4031228-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anti-protozoal activity | SYNTEX (U.S.A.) INC. (US) | 1977-06-21 | — | — | US | disclosed |
| US-4011320-A | PESTICIDES, FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1977-03-08 | — | — | US | disclosed |
| US-4005202-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1977-01-25 | — | — | US | disclosed |
| US-4002640-A | ANTIFUNGAL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-01-11 | — | — | US | disclosed |
| US-3993768-A | FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1976-11-23 | — | — | US | disclosed |
| US-3965113-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3962437-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-06-08 | — | — | US | disclosed |
| US-3935209-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-01-27 | — | — | US | disclosed |