Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 13/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575690 | 1.00 | ALDH1A1 (0.43) | ALDH1A1EPHX1ACHENPC1RAB9A | |
| SCHEMBL11631146 | 0.95 | EPHX1 (0.47) | ALDH1A1EPHX1ACHE | |
| SCHEMBL11631150 | 0.95 | EPHX1 (0.47) | ALDH1A1EPHX1ACHE | |
| SCHEMBL11626000 | 0.94 | EPHX1 (0.50) | EPHX1ACHE | |
| SCHEMBL11625997 | 0.94 | EPHX1 (0.50) | EPHX1ACHE | |
| SCHEMBL11403086 | 0.90 | MAPK1 (0.36) | ALDH1A1EPHX1ACHESMN1; SMN2HPGD | |
| SCHEMBL11280768 | 0.90 | MAPK1 (0.36) | ALDH1A1EPHX1ACHESMN1; SMN2HPGD | |
| SCHEMBL8058310 | 0.88 | ALDH1A1 (0.47) | ALDH1A1EPHX1ACHENPC1RAB9A | |
| SCHEMBL8058307 | 0.88 | ALDH1A1 (0.47) | ALDH1A1EPHX1ACHENPC1RAB9A | |
| SCHEMBL8058305 | 0.88 | ALDH1A1 (0.47) | ALDH1A1EPHX1ACHENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005961-A1 | COMPOUNDS HAVING A PLURALITY OF NITROGENOUS SUBSTITUENTS | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-12 | — | — | WO | disclosed |
| US-4312873-A | FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1982-01-26 | — | — | US | disclosed |
| US-4299837-A | IN ANIMALS | MONTEDISON S.P.A. (IT) | 1981-11-10 | — | — | US | disclosed |
| US-4191764-A | FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1980-03-04 | — | — | US | disclosed |
| US-4139626-A | FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4086235-A | PESTICIDES, ANTHELMINTICS, ANTIFUNGAL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4080461-A | PESTICIDES, FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1978-03-21 | — | — | US | disclosed |
| US-4031228-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anti-protozoal activity | SYNTEX (U.S.A.) INC. (US) | 1977-06-21 | — | — | US | disclosed |
| US-4011320-A | PESTICIDES, FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1977-03-08 | — | — | US | disclosed |
| US-4005202-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1977-01-25 | — | — | US | disclosed |
| US-4002640-A | ANTIFUNGAL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-01-11 | — | — | US | disclosed |
| US-3993768-A | FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1976-11-23 | — | — | US | disclosed |
| US-3965113-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3962437-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-06-08 | — | — | US | disclosed |
| US-3935209-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-01-27 | — | — | US | disclosed |