SCHEMBL11280773

SCHEMBL11280773

CCCC1CCC(c2ccc(-c3ccc(C(F)(F)C(F)(C(F)(F)F)C(F)(F)F)cc3)cc2)CC1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.49
MAPT P10636 1/20 0.49
CYP2C9 P11712 2/20 0.48
MEN1 O00255 1/20 0.46
MAPK1 P28482 1/20 0.46
KMT2A Q03164 1/20 0.46
ESR2 Q92731 3/20 0.38
DGAT1 O75907 4/20 0.36
SOAT1 P35610 2/20 0.36
HTR2C P28335 2/20 0.36
P2RY14 Q15391 4/20 0.35
ESR1 P03372 1/20 0.33
CYP3A4 P08684 1/20 0.33
KDM4E B2RXH2 1/20 0.32
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
IDO1 P14902 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11274726 0.92 ALDH1A1 (0.41) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL11284298 0.92 ALDH1A1 (0.51) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL11281201 0.91 MAPT (0.40) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL11275063 0.90 DGAT1 (0.39) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL11281602 0.90 MAPT (0.40) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL11277284 0.90 MAPT (0.40) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL11273913 0.90 MAPT (0.40) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL11280593 0.89 ALDH1A1 (0.49) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL11285016 0.88 ALDH1A1 (0.48) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL9074146 0.87 ALDH1A1 (0.50) ALDH1A1LMNAMAPTCYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0022183-B1 DERIVATIVES OF CYCLOHEXYLBIPHENYL, PROCESS FOR THEIR PREPARATION, DIELECTRICS CONTAINING THEM, AND ELECTRON OPTICAL INDICATING ELEMENTS MERCK PATENT GmbH (DE) 1982-06-23 EP disclosed
US-4330426-A Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-05-18 US disclosed
EP-0022183-A2 Derivatives of cyclohexylbiphenyl, process for their preparation, dielectrics containing them, and electron optical indicating elements MERCK PATENT GmbH (DE) 1981-01-14 EP disclosed