Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 12/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291917 | 0.90 | CACNA1F (0.52) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL11500635 | 0.87 | CACNA1B (0.46) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL10913858 | 0.85 | MEN1 (0.57) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL11106245 | 0.83 | CACNA1B (0.60) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11281855 | 0.83 | KDM4E (0.44) | CACNA1BMEN1KMT2ATSHRMAPT | |
| SCHEMBL10913259 | 0.81 | CACNA1C (0.55) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11005887 | 0.79 | CACNA1B (0.49) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11500155 | 0.79 | ALDH1A1 (0.44) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11276232 | 0.79 | TSHR (0.39) | CACNA1FCACNA1DCACNA1SCACNA1CCYP1A2 | |
| SCHEMBL11498937 | 0.79 | POLB (0.44) | MEN1KMT2ALMNATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011706-B1 | PROCESS FOR THE PREPARATION OF DERIVATIVES OF 1,4-DIHYDROPYRIDINE-3-CARBOXYLIC ACID, DERIVATIVES OF 1,4-DIHYDROPYRIDINE-3-CARBOXYLIC ACID AND THE USE OF THESE DERIVATIVES FOR THE PREPARATION OF 1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLATES | BAYER AG (DE) | 1982-03-03 | — | — | EP | disclosed |
| EP-0011706-A1 | Process for the preparation of derivatives of 1,4-dihydropyridine-3-carboxylic acid, derivatives of 1,4-dihydropyridine-3-carboxylic acid and the use of these derivatives for the preparation of 1,4-dihydropyridine-3,5-dicarboxylates | BAYER AG (DE) | 1980-06-11 | — | — | EP | disclosed |