Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28569559 | 0.83 | SMN1; SMN2 (0.51) | HPGDKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL4723219 | 0.80 | CNR2 (0.49) | KMT2ASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL5595476 | 0.79 | CYP1A2 (0.56) | HPGDKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL26670137 | 0.77 | SMN1; SMN2 (0.47) | HPGDKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL28555839 | 0.75 | SMN1; SMN2 (0.50) | HPGDKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5583370 | 0.74 | ALDH1A1 (0.52) | HPGDKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7802203 | 0.74 | SMN1; SMN2 (0.49) | HPGDKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7523694 | 0.74 | MEN1 (0.51) | HPGDKMT2AALDH1A1MEN1HTT | |
| SCHEMBL9584029 | 0.71 | PTPN1 (0.47) | HPGDKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6979799 | 0.70 | SMN1; SMN2 (0.42) | HPGDKMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309424-A | 4-Phenyl-1,3-benzodiazepines | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1982-01-05 | — | — | US | disclosed |