Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270598 | 0.90 | PLK1 (0.41) | CSNK2A1PLK1PLK3BRD4HPGD | |
| SCHEMBL13415965 | 0.86 | BRD4 (0.44) | CSNK2A1PLK1PLK3BRD4HPGD | |
| SCHEMBL8327546 | 0.83 | HTT (0.41) | CSNK2A1PLK1PLK3BRD4HPGD | |
| SCHEMBL1254852 | 0.80 | HPGD (0.39) | CSNK2A1PLK1PLK3BRD4HPGD | |
| SCHEMBL1266405 | 0.77 | CSNK2A1 (0.50) | CSNK2A1PLK1PLK3BRD4HPGD | |
| SCHEMBL8326599 | 0.76 | KDM4E (0.38) | CSNK2A1PLK1PLK3BRD4HPGD | |
| SCHEMBL7445206 | 0.75 | BRD4 (0.45) | CSNK2A1PLK1PLK3BRD4HPGD | |
| SCHEMBL7962458 | 0.75 | LMNA (0.36) | CSNK2A1PLK1PLK3BRD4HPGD | |
| SCHEMBL22916957 | 0.75 | TP53 (0.50) | BRD4HPGDSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11275611 | 0.74 | BRD4 (0.57) | CSNK2A1BRD4HPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336202-A | 1,3-Cyclohexanedione derivatives | KURARAY CO., LTD. (JP) | 1982-06-22 | — | — | US | disclosed |
| EP-0041656-A2 | Cyclohexanone derivatives and preparation thereof | KURARAY CO., LTD. (JP) | 1981-12-16 | — | — | EP | disclosed |