Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13415965 | 0.78 | BRD4 (0.44) | LMNABRD4PLK1CSNK2A1PLK3 | |
| SCHEMBL7440359 | 0.76 | HPGD (0.39) | LMNABRD4PLK1CSNK2A1PLK3 | |
| SCHEMBL11280877 | 0.75 | CSNK2A1 (0.44) | LMNABRD4PLK1CSNK2A1PLK3 | |
| SCHEMBL8327546 | 0.75 | HTT (0.41) | LMNABRD4PLK1CSNK2A1PLK3 | |
| SCHEMBL11275611 | 0.73 | BRD4 (0.57) | LMNABRD4CSNK2A1HPGDKMT2A | |
| SCHEMBL11270598 | 0.73 | PLK1 (0.41) | LMNABRD4PLK1CSNK2A1PLK3 | |
| SCHEMBL20780055 | 0.73 | SIGMAR1 (0.34) | POLB | |
| SCHEMBL1254852 | 0.72 | HPGD (0.39) | LMNABRD4PLK1CSNK2A1PLK3 | |
| SCHEMBL8326599 | 0.72 | KDM4E (0.38) | LMNABRD4PLK1CSNK2A1PLK3 | |
| SCHEMBL22916957 | 0.71 | TP53 (0.50) | LMNABRD4HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074803-A1 | METHOD FOR PREPARING 3-(4-HYDROXY-1H-INDOL-YLMETHYL)-PYRIDINIUM COMPOUNDS USING AN ALDOLISATION REACTION | L'OREAL (FR) | 2001-10-11 | — | — | WO | disclosed |
| WO-2001072739-A1 | METHOD FOR PREPARING 3-(4-HYDROXY-1H-INDOL-5-YLMETHYL)-PYRIDINIUM COMPOUNDS VIA ENONES | L'OREAL (FR) | 2001-10-04 | — | — | WO | disclosed |
| US-4336202-A | 1,3-Cyclohexanedione derivatives | KURARAY CO., LTD. (JP) | 1982-06-22 | — | — | US | disclosed |
| EP-0041656-A2 | Cyclohexanone derivatives and preparation thereof | KURARAY CO., LTD. (JP) | 1981-12-16 | — | — | EP | disclosed |