SCHEMBL11280912

SCHEMBL11280912

Cc1ccc(-c2ccc(C3CCC(C)CC3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.59
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SLC18A3 Q16572 1/20 0.41
PKM P14618 1/20 0.39
EBP Q15125 1/20 0.39
DHCR7 Q9UBM7 1/20 0.39
MAPT P10636 4/20 0.38
LMNA P02545 3/20 0.38
ATM Q13315 2/20 0.38
TP53 P04637 2/20 0.38
ALDH1A1 P00352 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 3/20 0.37
P2RY14 Q15391 1/20 0.36
MEN1 O00255 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19937427 0.94 ESR2 (0.65) ESR2RAB9ASLC18A3PKMMAPT
SCHEMBL24597681 0.94 ESR2 (0.65) ESR2RAB9ASLC18A3PKMMAPT
SCHEMBL11187396 0.91 ESR2 (0.68) ESR2NPC1RAB9AMAPTKMT2A
SCHEMBL11187392 0.91 ESR2 (0.68) ESR2NPC1RAB9AMAPTKMT2A
SCHEMBL17666384 0.88 ESR2 (0.59) ESR2RAB9ASLC18A3PKMMAPT
SCHEMBL4549765 0.84 ESR2 (0.47) ESR2NPC1RAB9ASLC18A3PKM
SCHEMBL11196166 0.84 ESR2 (0.77) ESR2NPC1RAB9ASLC18A3
SCHEMBL1405569 0.84 ESR2 (0.50) ESR2RAB9ASLC18A3MAPTLMNA
SCHEMBL10091206 0.83 NPC1 (0.59) ESR2NPC1RAB9ASLC18A3HRH3
SCHEMBL10091174 0.83 NPC1 (0.59) ESR2NPC1RAB9ASLC18A3HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021253627-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT, AND LIQUID CRYSTAL DISPLAY 石家庄诚志永华显示材料有限公司 2021-12-23 WO disclosed
WO-2020121639-A1 POLYMERIZABLE COMPOUND-CONTAINING LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY DEVICE, AND POLYMERIZABLE COMPOUND DIC株式会社 2020-06-18 WO disclosed
WO-2020116555-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC株式会社 2020-06-11 WO disclosed
WO-2020044833-A1 LIQUID CRYSTAL COMPOSITION DIC株式会社 2020-03-05 WO disclosed
WO-2020026831-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC株式会社 2020-02-06 WO disclosed
US-10344211-B2 Liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2019-07-09 US disclosed
US-10208250-B2 Liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2019-02-19 US disclosed
US-9963636-B2 Liquid crystal composition and liquid crystal display device using same DIC CORPORATION (JP) 2018-05-08 US disclosed
US-20170355906-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-12-14 US disclosed
US-20170029700-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-02-02 US disclosed
EP-0022183-B1 DERIVATIVES OF CYCLOHEXYLBIPHENYL, PROCESS FOR THEIR PREPARATION, DIELECTRICS CONTAINING THEM, AND ELECTRON OPTICAL INDICATING ELEMENTS MERCK PATENT GmbH (DE) 1982-06-23 EP disclosed
US-4330426-A Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-05-18 US disclosed
EP-0022183-A2 Derivatives of cyclohexylbiphenyl, process for their preparation, dielectrics containing them, and electron optical indicating elements MERCK PATENT GmbH (DE) 1981-01-14 EP disclosed