SCHEMBL19937427

SCHEMBL19937427

Cc1ccc(C2CCC(C)CC2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 3/20 0.65
SLC18A3 Q16572 1/20 0.44
PKM P14618 1/20 0.41
MAPT P10636 2/20 0.41
ATM Q13315 2/20 0.41
LMNA P02545 2/20 0.41
TP53 P04637 2/20 0.41
ALDH1A1 P00352 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
ACHE P22303 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
POLB P06746 1/20 0.38
MAP1LC3B Q9GZQ8 1/20 0.38
CYP3A4 P08684 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
HTT P42858 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24597681 1.00 ESR2 (0.65) ESR2SLC18A3PKMMAPTATM
SCHEMBL17666384 0.94 ESR2 (0.59) ESR2SLC18A3PKMMAPTATM
SCHEMBL11280912 0.94 ESR2 (0.59) ESR2SLC18A3PKMMAPTATM
SCHEMBL1405569 0.90 ESR2 (0.50) ESR2SLC18A3MAPTATMLMNA
SCHEMBL11196166 0.90 ESR2 (0.77) ESR2SLC18A3POLBCYP3A4CYP2C9
SCHEMBL10696260 0.88 ESR2 (0.53) ESR2SLC18A3PKMMAPTATM
SCHEMBL14231502 0.88 ESR2 (0.53) ESR2SLC18A3PKMMAPTATM
SCHEMBL24721229 0.87 ESR2 (0.52) ESR2SLC18A3PKMMAPTATM
SCHEMBL16892913 0.86 ESR2 (0.50) ESR2SLC18A3PKMMAPTATM
SCHEMBL7792381 0.84 SMN1; SMN2 (0.57) ESR2SLC18A3PKMMAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230313043-A1 OPTICAL COMPONENT MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
US-20230053362-A1 DICHROIC DYE COMPOSITION MERCK PATENT GMBH (DE) 2023-02-23 US disclosed
EP-4137552-A1 LIQUID CRYSTAL COMPOSITION HAVING EXTREMELY LOW DIELECTRIC LOSS, AND HIGH-FREQUENCY COMPONENT COMPRISING SAME Xi'an Modern Chemistry Research Institute (CN) 2023-02-22 EP disclosed
US-11168257-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2021-11-09 US disclosed
EP-3442932-B1 PRODUCTION OF METHYL-SUBSTITUTED BIPHENYL COMPOUNDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-11-20 EP disclosed
US-20190203137-A1 LOW TRACTION/ENERGY EFFICIENT LIQUID CRYSTAL BASE STOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2019-07-04 US disclosed
US-20190203138-A1 PHASE CHANGE MATERIALS FOR ENHANCED HEAT TRANSFER FLUID PERFORMANCE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2019-07-04 US disclosed
US-20190153320-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-05-23 US disclosed
US-20190031958-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2019-01-31 US disclosed
US-20180163136-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-06-14 US disclosed
EP-2514800-B2 Compounds and liquid crystalline medium MERCK PATENT GMBH (DE) 2018-03-07 EP disclosed