Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 5/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19937427 | 0.90 | ESR2 (0.65) | ESR2SLC18A3ACHETDP1ALDH1A1 | |
| SCHEMBL24597681 | 0.90 | ESR2 (0.65) | ESR2SLC18A3ACHETDP1ALDH1A1 | |
| SCHEMBL43080 | 0.89 | SLC18A3 (0.56) | ESR2SLC18A3ACHETDP1ALDH1A1 | |
| SCHEMBL2537599 | 0.89 | SLC18A3 (0.52) | ESR2SLC18A3ACHETDP1ALDH1A1 | |
| Bicarbonate SCHEMBL1720129 | 0.88 | NPC1 (0.48) | ESR2SLC18A3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12675264 | 0.88 | ESR2 (0.69) | ESR2ACHEESR1CYP3A4CYP2C9 | |
| SCHEMBL10062044 | 0.88 | ESR2 (0.65) | ESR2SLC18A3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21531821 | 0.88 | SLC18A3 (0.43) | ESR2SLC18A3ACHETDP1ALDH1A1 | |
| SCHEMBL8594522 | 0.88 | SLC18A3 (0.47) | ESR2SLC18A3ACHETDP1ALDH1A1 | |
| SCHEMBL19033731 | 0.88 | SPHK1 (0.51) | ESR2SLC18A3ACHETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3363788-A1 | CANNABINOID RECEPTOR MODULATORS | Arena Pharmaceuticals, Inc. (US) | 2018-08-22 | — | — | EP | claimed |
| CN-105593214-B | Method for synthesizing N-benzyl-N-cyclopropyl-1H-pyrazole-4-formamide derivative | 拜耳作物科学股份公司 | 2018-05-29 | — | — | CN | claimed |
| US-20130165412-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. | 2013-06-27 | — | — | US | claimed |
| US-20120214766-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. | 2012-08-23 | — | — | US | claimed |
| US-20080293701-A1 | 1-Acylamino-2-Hydroxy-3-Amino- -Arylalkanes as Renin Inhibitors | VITAE PHARMACEUTICALS, INC. | 2008-11-27 | — | — | US | claimed |
| EP-1844002-A1 | 1-ACYLAMINO-2-HYDROXY-3-AMINO-W-ARYLALKANES AS RENIN INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2007-10-17 | — | — | EP | claimed |
| WO-2006083924-A1 | 1-ACYLAMINO-2-HYDROXY-3-AMINO-W-ARYLALKANES AS RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2006-08-10 | — | — | WO | claimed |
| US-20260007684-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U S INC (US) | 2026-01-08 | — | — | US | disclosed |
| CN-118978472-A | Preparation method of indolone compound connected with gamma-ketosulfone structure | 安阳师范学院 | 2024-11-19 | — | — | CN | disclosed |
| US-11771695-B2 | Cannabinoid receptor modulators | ARENA PHARMACEUTICALS, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-11746091-B2 | Cannabinoid receptor modulators | ARENA PHARMACEUTICALS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| US-20220241274-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. | 2022-08-04 | — | — | US | disclosed |
| CN-109970708-B | Cannabinoid receptor modulators | 艾尼纳制药公司 | 2022-06-21 | — | — | CN | disclosed |
| EP-0384785-B1 | Process for preparing superconductive fibers of high density | DU PONT (US) | 1993-12-29 | — | — | EP | disclosed |
| WO-1993015100-A1 | NOVEL ADENOSINE DERIVATIVES, THEIR PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRES UPSA (FR) | 1993-08-05 | — | — | WO | disclosed |
| US-5100864-A | PROCESS FOR PREPARING SUPERCONDUCTIVE FIBERS OF HIGH DENSITY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-31 | — | — | US | disclosed |
| US-5051447-A | Applying aromatic oximes to plants, seeds or soils | BASF AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |
| EP-0384785-A2 | Process for preparing superconductive fibers of high density | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |
| US-4952720-A | Ortho-substituted benzyl carboxylates and fungicides which contain these compounds | BASF AKTIENGSELLSCHAFT (DE) | 1990-08-28 | — | — | US | disclosed |
| US-4019890-A | SPRAY COATING, GELATION; SLOW-RELEASE GRANULES | CHISSOASAHI FERTILIZER CO., LTD. (JA) | 1977-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214766-A1 | CANNABINOID RECEPTOR MODULATORS | CNR1, CNR2, TRPV1 | ESR2 1008/4885SLC18A3 2946/4885ACHE 136/4885 |
| US-11746091-B2 | Cannabinoid receptor modulators | CNR1, CNR2, TRPV1 | ESR2 1008/4885SLC18A3 2946/4885ACHE 136/4885 |
| US-20220241274-A1 | CANNABINOID RECEPTOR MODULATORS | CNR2, CNR1, OPRL1 | ESR2 395/4885SLC18A3 1052/4885ACHE 410/4885 |
| US-20260007684-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | NOD1, NLRP3, NOD2 | ESR2 1609/4885SLC18A3 4500/4885ACHE 4749/4885 |
| US-11771695-B2 | Cannabinoid receptor modulators | CNR2, CNR1, OPRL1 | ESR2 395/4885SLC18A3 1052/4885ACHE 410/4885 |
| US-20080293701-A1 | 1-Acylamino-2-Hydroxy-3-Amino- -Arylalkanes as Renin Inhibitors | REN, AGTR1, AGTR2 | ESR2 1374/4885SLC18A3 1822/4885ACHE 1824/4885 |
| US-20130165412-A1 | CANNABINOID RECEPTOR MODULATORS | CNR1, CNR2, TRPV1 | ESR2 1008/4885SLC18A3 2946/4885ACHE 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.