SCHEMBL11282137

SCHEMBL11282137

CCSN1C(=O)C(=C2c3ccccc3-c3c2cc([N+](=O)[O-])cc3[N+](=O)[O-])C(=O)N(SCC)C1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
ALDH1A1 P00352 1/20 0.38
GLA P06280 1/20 0.38
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
CTDSP1 Q9GZU7 1/20 0.37
HSP90AA1 P07900 2/20 0.37
HPRT1 P00492 1/20 0.36
PTPRC P08575 2/20 0.36
S100A4 P26447 1/20 0.36
FTO Q9C0B1 2/20 0.35
PABPC1 P11940 2/20 0.35
POLB P06746 1/20 0.35
S1PR1 P21453 1/20 0.35
HTT P42858 1/20 0.35
RAD52 P43351 1/20 0.35
RECQL P46063 1/20 0.35
RAB9A P51151 1/20 0.35
PAX8 Q06710 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11286251 0.91 HPRT1 (0.43) ALDH1A1MEN1KMT2ACTDSP1HSP90AA1
SCHEMBL11290539 0.91 HKDC1 (0.40) KDM4EMAPTALDH1A1GLAMEN1
SCHEMBL11285507 0.88 MEN1 (0.39) KDM4EMAPTALDH1A1GLAMEN1
SCHEMBL11276864 0.85 PTPRC (0.40) ALDH1A1MEN1KMT2ACTDSP1HSP90AA1
SCHEMBL11280203 0.83 HPRT1 (0.39) KDM4EMAPTALDH1A1GLAMEN1
SCHEMBL11285382 0.81 PTPRC (0.43) KDM4EALDH1A1HSP90AA1PTPRCS100A4
SCHEMBL11285425 0.79 PTPRC (0.44) KDM4EMAPTALDH1A1MEN1KMT2A
SCHEMBL11282135 0.79 MEN1 (0.40) KDM4EMAPTALDH1A1GLAMEN1
SCHEMBL11292899 0.79 HPRT1 (0.46) ALDH1A1MEN1KMT2ACTDSP1HSP90AA1
SCHEMBL11281196 0.78 HKDC1 (0.42) KDM4EMAPTALDH1A1GLAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4349618-A 5-DIPHENYLMETHYLENE- OR 5-(FLUOREN-9-YLIDENE) THIOBARBITURIC ACID AND DERIVATIVES AS SENSITIZERS FOR N-VVINYLCARBAZOLE POLYMERS; ELECTROPHORESIS FUJI PHOTO FILM CO., LTD. (JP) 1982-09-14 US claimed
US-4349618-A 5-DIPHENYLMETHYLENE- OR 5-(FLUOREN-9-YLIDENE) THIOBARBITURIC ACID AND DERIVATIVES AS SENSITIZERS FOR N-VVINYLCARBAZOLE POLYMERS; ELECTROPHORESIS FUJI PHOTO FILM CO., LTD. (JP) 1982-09-14 US disclosed