SCHEMBL11285507

SCHEMBL11285507

CSN1C(=O)C(=C2c3ccccc3-c3c2cc([N+](=O)[O-])cc3[N+](=O)[O-])C(=O)N(SC)C1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
HSP90AA1 P07900 2/20 0.39
PTPRC P08575 3/20 0.38
S100A4 P26447 2/20 0.38
HPRT1 P00492 1/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GLA P06280 1/20 0.38
MAPT P10636 1/20 0.38
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36
HKDC1 Q2TB90 1/20 0.36
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35
CES1 P23141 1/20 0.35
SCN2A Q99250 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11292899 0.91 HPRT1 (0.46) MEN1KMT2ACTDSP1HSP90AA1PTPRC
SCHEMBL11281196 0.90 HKDC1 (0.42) MEN1KMT2ACTDSP1HSP90AA1HPRT1
SCHEMBL11282137 0.88 KDM4E (0.38) MEN1KMT2ACTDSP1HSP90AA1PTPRC
SCHEMBL11280203 0.86 HPRT1 (0.39) MEN1KMT2ACTDSP1HSP90AA1PTPRC
SCHEMBL11285237 0.84 PTPRC (0.42) MEN1KMT2ACTDSP1HSP90AA1PTPRC
SCHEMBL11285541 0.80 HPRT1 (0.45) MEN1KMT2ACTDSP1HSP90AA1PTPRC
SCHEMBL11285502 0.80 NR1H2 (0.42) MEN1KMT2ACTDSP1HSP90AA1PTPRC
SCHEMBL11283800 0.80 ALDH1A1 (0.41) MEN1KMT2ACTDSP1HSP90AA1PTPRC
SCHEMBL11280059 0.80 PTPRC (0.46) MEN1KMT2APTPRCS100A4ALDH1A1
SCHEMBL11286251 0.79 HPRT1 (0.43) MEN1KMT2ACTDSP1HSP90AA1PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4349618-A 5-DIPHENYLMETHYLENE- OR 5-(FLUOREN-9-YLIDENE) THIOBARBITURIC ACID AND DERIVATIVES AS SENSITIZERS FOR N-VVINYLCARBAZOLE POLYMERS; ELECTROPHORESIS FUJI PHOTO FILM CO., LTD. (JP) 1982-09-14 US disclosed