Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 18/20 | 0.46 |
| ▸ | CNR2 | P34972 | 14/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1986300 | 0.77 | CYP2C19 (0.47) | CNR1CNR2 | |
| SCHEMBL1988812 | 0.72 | CHRNA7 (0.47) | CNR1CNR2 | |
| SCHEMBL1988289 | 0.71 | ALDH1A1 (0.44) | CNR1CNR2 | |
| SCHEMBL5795128 | 0.71 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL12563350 | 0.70 | CYP2C19 (0.43) | CNR1CNR2 | |
| SCHEMBL1128119 | 0.69 | CNR1 (0.42) | CNR1CNR2 | |
| SCHEMBL1989867 | 0.69 | CYP2C19 (0.42) | CNR1CNR2 | |
| SCHEMBL1985661 | 0.67 | CYP2C19 (0.40) | CNR1CNR2 | |
| SCHEMBL12563354 | 0.66 | CNR1 (0.54) | CNR1CNR2 | |
| SCHEMBL5922332 | 0.65 | CNR1 (0.67) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283007-A2 | PYRROLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC APPLICATION THEREOF | Sanofi-aventis (FR) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009141532-A2 | PYRROLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2009-11-26 | — | — | WO | disclosed |