SCHEMBL1128119

SCHEMBL1128119

Cn1c(C(=O)NC(=O)C2(N3CCCCC3)CCNCC2)cc(-c2ccc(Cl)cc2Cl)c1-c1ccc(O)cc1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 10/20 0.42
CNR2 P34972 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2569129 0.86 CNR1 (0.38) CNR1
SCHEMBL1128278 0.86 CNR1 (0.39) CNR1
SCHEMBL1127889 0.82 CNR1 (0.40) CNR1CNR2
SCHEMBL1128121 0.77 CNR1 (0.56) CNR1
SCHEMBL5795128 0.73 CNR1 (0.64) CNR1CNR2
SCHEMBL1260019 0.73 CNR1 (0.68) CNR1CNR2
SCHEMBL1260541 0.72 CNR1 (0.60) CNR1
SCHEMBL2570109 0.71 ESR1 (0.51) CNR1
SCHEMBL1128271 0.69 CNR1 (0.46) CNR1CNR2
SCHEMBL1260985 0.69 CNR1 (0.59) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2283008-A2 PYRROLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC APPLICATION THEREOF Sanofi-aventis (FR) 2011-02-16 EP disclosed
WO-2009141533-A2 PYRROLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC APPLICATION THEREOF SANOFI-AVENTIS (FR) 2009-11-26 WO disclosed