SCHEMBL11282829

SCHEMBL11282829

CC(C)CC1C/C(=C/c2ccc(N)cc2)C(=O)/C(=C/c2ccc(N)cc2)C1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.44
RAB9A P51151 5/20 0.44
NPC1 O15118 4/20 0.44
HTT P42858 4/20 0.44
MAPK1 P28482 3/20 0.44
HSP90AA1 P07900 2/20 0.44
LMNA P02545 4/20 0.41
ALDH1A1 P00352 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAOB P27338 1/20 0.39
F2 P00734 7/20 0.38
F10 P00742 6/20 0.38
PLAU P00749 1/20 0.38
PLAT P00750 1/20 0.38
MITF O75030 1/20 0.38
NSD2 O96028 1/20 0.38
ATM Q13315 1/20 0.38
USP18 Q9UMW8 1/20 0.38
UCHL5 Q9Y5K5 1/20 0.38
BCHE P06276 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11282830 1.00 MAPT (0.44) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL11291343 0.87 MAPT (0.41) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL11291340 0.87 MAPT (0.41) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL10977512 0.83 MAPT (0.57) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL10977516 0.83 MAPT (0.57) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL18415114 0.83 MAPT (0.57) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL10977635 0.81 MAPT (0.65) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL21028263 0.81 MAPT (0.65) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL10977632 0.81 MAPT (0.65) MAPTRAB9ANPC1HTTMAPK1
SCHEMBL11286592 0.81 MAPT (0.42) MAPTRAB9ANPC1HTTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4354976-A Process for the preparation of azidobenzal compounds MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-10-19 US disclosed