SCHEMBL21028263

SCHEMBL21028263

CC1C/C(=C\c2ccc(N)cc2)C(=O)/C(=C/c2ccc(N)cc2)C1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.65
NPC1 O15118 5/20 0.65
RAB9A P51151 5/20 0.65
MAPK1 P28482 3/20 0.65
HTT P42858 3/20 0.65
HSP90AA1 P07900 1/20 0.65
LMNA P02545 4/20 0.54
MITF O75030 1/20 0.54
NSD2 O96028 1/20 0.54
ATM Q13315 1/20 0.54
MEN1 O00255 6/20 0.50
KMT2A Q03164 6/20 0.50
ALDH1A1 P00352 3/20 0.49
PKM P14618 2/20 0.49
POLB P06746 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KDM4E B2RXH2 2/20 0.47
NPSR1 Q6W5P4 2/20 0.47
XBP1 P17861 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10977632 1.00 MAPT (0.65) MAPTNPC1RAB9AMAPK1HTT
SCHEMBL10977635 1.00 MAPT (0.65) MAPTNPC1RAB9AMAPK1HTT
SCHEMBL15436912 0.84 MAPT (0.67) MAPTNPC1RAB9AMAPK1HTT
SCHEMBL9006499 0.83 MAPT (0.47) MAPTNPC1RAB9AMAPK1HTT
SCHEMBL9006491 0.83 MAPT (0.47) MAPTNPC1RAB9AMAPK1HTT
SCHEMBL9448683 0.82 MAPT (0.65) MAPTNPC1RAB9AMAPK1HTT
SCHEMBL9448690 0.82 MAPT (0.65) MAPTNPC1RAB9AMAPK1HTT
SCHEMBL17899528 0.82 MAPT (0.65) MAPTNPC1RAB9AMAPK1HTT
SCHEMBL14012043 0.81 MAPT (0.69) MAPTNPC1RAB9AMAPK1HTT
SCHEMBL16807421 0.81 MAPT (0.69) MAPTNPC1RAB9AMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11780790-B2 Organic light emitting device, crosslinking agent compound for organic light emitting device and manufacturing method of the organic light emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-10 US disclosed
EP-3941167-A1 THIN METAL ELECTRODE FILMS, AND MANUFACTURING METHOD THEREOF BASF SE (DE) 2022-01-19 EP disclosed
US-20210347714-A1 ORGANIC LIGHT EMITTING DEVICE, CROSSLINKING AGENT COMPOUND FOR ORGANIC LIGHT EMITTING DEVICE AND MANUFACTURING METHOD OF THE ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-11 US disclosed
US-20210226142-A1 UV CROSSLINKING OF PVDF-BASED POLYMERS FOR GATE DIELECTRIC INSULATORS OF ORGANIC THIN-FILM TRANSISTORS CORNING INCORPORATED 2021-07-22 US disclosed
US-20200203612-A1 AZIDE-BASED COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE AZIDE-BASED COMPOUND, AND METHOD OF MANUFACTURING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-06-25 US disclosed
US-10415011-B2 Adherend recovery method, adherend recovery apparatus, gas-generating film and resin composition JSR CORPORATION (JP) 2019-09-17 US disclosed
US-10300477-B2 Terminally-crosslinked methyl morpholinium-functionalized block copolymers, and anion exchange membranes using the same INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION (KR) 2019-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11780790-B2 Organic light emitting device, crosslinking agent compound for organic light emitting device and manufacturing method of the organic light emitting device CYBA, AOX1, GJA1 MAPT 904/4885NPC1 1964/4885RAB9A 2798/4885
US-20210347714-A1 ORGANIC LIGHT EMITTING DEVICE, CROSSLINKING AGENT COMPOUND FOR ORGANIC LIGHT EMITTING DEVICE AND MANUFACTURING METHOD OF THE ORGANIC LIGHT EMITTING DEVICE CYBA, AOX1, GJA1 MAPT 904/4885NPC1 1964/4885RAB9A 2798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.