Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271085 | 0.83 | ALDH1A1 (0.52) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL11275890 | 0.82 | ALDH1A1 (0.51) | MEN1KMT2AKDM4EALDH1A1CA12 | |
| SCHEMBL11272196 | 0.82 | ALDH1A1 (0.54) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL11277993 | 0.81 | ALDH1A1 (0.52) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL11279025 | 0.80 | ALDH1A1 (0.51) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL11279531 | 0.74 | ALDH1A1 (0.48) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL11282506 | 0.74 | ALDH1A1 (0.51) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL22605349 | 0.73 | KDM4E (0.61) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL9157389 | 0.72 | KDM4E (0.51) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL11277508 | 0.70 | KDM4E (0.58) | MEN1KMT2AKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337265-A | COMPLICATIONS OF DIABETES | AYERST, MCKENNA & HARRISON INC. (CA) | 1982-06-29 | — | — | US | disclosed |