Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272994 | 0.80 | L3MBTL1 (0.53) | KDM4EALDH1A1L3MBTL1TSHRHPGD | |
| SCHEMBL1987381 | 0.79 | CYP1A2 (0.56) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4859201 | 0.79 | HTT (0.56) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11183792 | 0.78 | KDM4E (0.73) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8269503 | 0.75 | BACE1 (0.56) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1987535 | 0.74 | RAB9A (0.54) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7214682 | 0.74 | ALDH1A1 (0.56) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7214687 | 0.74 | ALDH1A1 (0.56) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7214686 | 0.74 | ALDH1A1 (0.56) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1987140 | 0.73 | RAB9A (0.53) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337265-A | COMPLICATIONS OF DIABETES | AYERST, MCKENNA & HARRISON INC. (CA) | 1982-06-29 | — | — | US | disclosed |