Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HTR3A | P46098 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281948 | 0.81 | LMNA (0.44) | KMT2AHTR2CKDM4EHPGDALDH1A1 | |
| SCHEMBL11426226 | 0.81 | GBA1 (0.45) | KMT2AHTR2CKDM4EHPGDALDH1A1 | |
| SCHEMBL11280239 | 0.81 | HTR2C (0.64) | KMT2AHTR2CHRH4KDM4EHPGD | |
| SCHEMBL11285567 | 0.80 | KDM4E (0.41) | KMT2AHTR2CHRH4KDM4EHTR3A | |
| SCHEMBL11278787 | 0.80 | SMN1; SMN2 (0.49) | KMT2AKDM4EHPGDALDH1A1ACHE | |
| Hydrochloric Acid SCHEMBL11292638 | 0.79 | HTR2C (0.62) | KMT2AHTR2CHRH4KDM4EHPGD | |
| SCHEMBL11282952 | 0.79 | HTR2C (0.62) | KMT2AHTR2CHRH4KDM4EHPGD | |
| SCHEMBL11402503 | 0.79 | HTR2C (0.71) | KMT2AHTR2CHRH4KDM4EHPGD | |
| SCHEMBL11278582 | 0.79 | HTR2C (0.58) | HTR2CHRH4KDM4EHTR3AHPGD | |
| SCHEMBL11284746 | 0.79 | HSD17B10 (0.42) | KMT2AHTR2CKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |