Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | CYBB | P04839 | 1/20 | 0.46 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.46 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.46 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | C1S | P09871 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287133 | 0.86 | ALDH1A1 (0.50) | SMN1; SMN2HSD17B10KDM4EHPGDDHFR | |
| SCHEMBL11290070 | 0.86 | HSD17B10 (0.64) | SMN1; SMN2HSD17B10KDM4EHPGDDHFR | |
| SCHEMBL11388114 | 0.83 | HTR2C (0.61) | SMN1; SMN2HSD17B10KDM4EHPGDCYBB | |
| SCHEMBL11282888 | 0.82 | PKM (0.50) | SMN1; SMN2KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL11387692 | 0.80 | HTR2C (0.58) | SMN1; SMN2HSD17B10KDM4EHPGDCYBB | |
| SCHEMBL11289296 | 0.80 | HSD17B10 (0.45) | SMN1; SMN2HSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL11283262 | 0.80 | KMT2A (0.50) | KDM4EHPGDALDH1A1ACHEKMT2A | |
| SCHEMBL6665691 | 0.76 | DHFR (0.51) | KDM4ECYBBNOX5NOX3NOX4 | |
| SCHEMBL11281948 | 0.74 | LMNA (0.44) | SMN1; SMN2HSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL11426226 | 0.74 | GBA1 (0.45) | SMN1; SMN2KDM4EHPGDALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |