Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 3/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283267 | 1.00 | F3 (0.57) | F3HSD11B1CYP2D6CYP2C9TYR | |
| SCHEMBL18758181 | 0.93 | FOS (0.59) | F3HSD11B1CYP2D6CYP2C9TYR | |
| SCHEMBL11146177 | 0.88 | HSD17B3 (0.77) | CYP2D6LMNASMN1; SMN2MAPTMAOB | |
| SCHEMBL11146179 | 0.88 | HSD17B3 (0.77) | CYP2D6LMNASMN1; SMN2MAPTMAOB | |
| SCHEMBL9353382 | 0.86 | TDP1 (0.59) | CYP2C9LMNASMN1; SMN2MAPTMAOB | |
| SCHEMBL309763 | 0.86 | HCAR2 (0.59) | CYP2D6TYRLMNASMN1; SMN2MAPT | |
| SCHEMBL9353385 | 0.86 | TDP1 (0.59) | CYP2C9LMNASMN1; SMN2MAPTMAOB | |
| SCHEMBL765933 | 0.86 | HCAR2 (0.59) | CYP2D6TYRLMNASMN1; SMN2MAPT | |
| SCHEMBL6836595 | 0.84 | LMNA (0.56) | CYP2C9LMNASMN1; SMN2MAPTMAOB | |
| Hydrochloric Acid SCHEMBL11763321 | 0.84 | HCAR2 (0.57) | CYP2D6TYRLMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349553-A | Spiro-cyclopropyl amidinohydrazones, and use as insect and fire ant control agents | AMERICAN CYANAMID COMPANY (US) | 1982-09-14 | — | — | US | disclosed |
| US-RE29358-E | ANTI-MALARIA AND ANTI-TUBERCULOSIS AGENTS | AMERICAN CYANAMID COMPANY (US) | 1977-08-16 | — | — | US | disclosed |