SCHEMBL765933

SCHEMBL765933

CCc1ccc(/C=C/C(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.59
ESR1 P03372 2/20 0.59
ESR2 Q92731 2/20 0.59
CA12 O43570 1/20 0.59
AKR1B10 O60218 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
CA3 P07451 1/20 0.59
PKM P14618 1/20 0.59
TYR P14679 1/20 0.59
AKR1B1 P15121 1/20 0.59
CA4 P22748 1/20 0.59
CA6 P23280 1/20 0.59
DPP4 P27487 1/20 0.59
CA5A P35218 1/20 0.59
CA7 P43166 1/20 0.59
CA9 Q16790 1/20 0.59
CA14 Q9ULX7 1/20 0.59
CA5B Q9Y2D0 1/20 0.59
HDAC3 O15379 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL309763 1.00 HCAR2 (0.59) HCAR2ESR1ESR2CA12AKR1B10
Hydrochloric Acid SCHEMBL11763321 0.98 HCAR2 (0.57) HCAR2ESR1ESR2CA12AKR1B10
Bicarbonate SCHEMBL867321 0.98 HCAR2 (0.57) HCAR2ESR1ESR2CA12AKR1B10
SCHEMBL23512479 0.94 KDM4E (0.57) HCAR2ESR1ESR2CA12AKR1B10
SCHEMBL7957010 0.94 KDM4E (0.57) HCAR2ESR1ESR2CA12AKR1B10
SCHEMBL7957004 0.94 KDM4E (0.57) HCAR2ESR1ESR2CA12AKR1B10
Methacrylic Acid SCHEMBL10714814 0.90 HCAR2 (0.49) HCAR2ESR1ESR2CA12AKR1B10
SCHEMBL11283267 0.86 F3 (0.57) TYRKDM4EPTGS2SMN1; SMN2MAOB
SCHEMBL11283271 0.86 F3 (0.57) TYRKDM4EPTGS2SMN1; SMN2MAOB
SCHEMBL1206716 0.85 KDM4E (0.67) HCAR2ESR1ESR2CA12AKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12365830-B2 Ligand-exchangeable janus nanoparticles and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2025-07-22 US claimed
US-20220259490-A1 LIGAND-EXCHANGEABLE JANUS NANOPARTICLES AND METHODS OF MAKING THE SAME Alliance for Energy Innovation, LLC 2022-08-18 US claimed
WO-2020252075-A1 LIGAND-EXCHANGEABLE JANUS NANOPARTICLES AND METHODS OF MAKING THE SAME ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2020-12-17 WO claimed
US-10544168-B2 Ligand-exchangeable nanoparticles and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2020-01-28 US claimed
US-20170362255-A1 LIGAND-EXCHANGEABLE NANOPARTICLES AND METHODS OF MAKING THE SAME Alliance for Energy Innovation, LLC 2017-12-21 US claimed
US-12365830-B2 Ligand-exchangeable janus nanoparticles and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2025-07-22 US disclosed
US-20220259490-A1 LIGAND-EXCHANGEABLE JANUS NANOPARTICLES AND METHODS OF MAKING THE SAME Alliance for Energy Innovation, LLC 2022-08-18 US disclosed
CN-112608275-A Application of 2, 8-bis (trifluoromethyl) -4-hydroxyquinoline derivative in preparation and prevention and treatment of agricultural diseases 兰州大学 2021-04-06 CN disclosed
WO-2020252075-A1 LIGAND-EXCHANGEABLE JANUS NANOPARTICLES AND METHODS OF MAKING THE SAME ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2020-12-17 WO disclosed
US-10544168-B2 Ligand-exchangeable nanoparticles and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2020-01-28 US disclosed
EP-2822938-B1 RODENTICIDAL NORBORMIDE ANALOGUES LANDCARE RES NEW ZEALAND LIMITED (NZ) 2019-07-03 EP disclosed
US-20170362255-A1 LIGAND-EXCHANGEABLE NANOPARTICLES AND METHODS OF MAKING THE SAME Alliance for Energy Innovation, LLC 2017-12-21 US disclosed
US-4328355-A ANTIFERTILITY AGENTS G. D. SEARLE & CO. (US) 1982-05-04 US disclosed
US-4070484-A Antiallergic composition containing aromatic carboxylic amide derivatives and method of using the same KISSEI PHARMACEUTICAL CO., LTD. (JA) 1978-01-24 US disclosed
US-4061587-A Liquid crystalline cinnamic acid esters HOFFMANN-LA ROCHE INC. (US) 1977-12-06 US disclosed
US-4026896-A ANTIALLERGENS KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (KISSEI PHARMACEUTICAL CO. LTD.) (JA) 1977-05-31 US disclosed
US-3995054-A MITICIDES ZOECON CORPORATION (US) 1976-11-30 US disclosed
US-3975429-A Cyclopropanemethyl esters of cinnamic acid and derivatives thereof ZOECON CORPORATION (US) 1976-08-17 US disclosed
US-3962219-A DISTYRYL-BENZOBISOXAZOLES BAYER AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed
US-3940422-A ANTIALLERGEN KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (JA) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10544168-B2 Ligand-exchangeable nanoparticles and methods of making the same CA6, CA13, EPCAM HCAR2 11/4885ESR1 39/4885ESR2 651/4885
US-20170362255-A1 LIGAND-EXCHANGEABLE NANOPARTICLES AND METHODS OF MAKING THE SAME CA6, CA13, EPCAM HCAR2 11/4885ESR1 39/4885ESR2 651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.