⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448689 | 0.75 | NPC1 (0.36) | — | |
| SCHEMBL2235642 | 0.72 | KDM4C (0.44) | — | |
| SCHEMBL755723 | 0.70 | — | — | |
| SCHEMBL16910470 | 0.70 | KDM4C (0.49) | — | |
| SCHEMBL6294711 | 0.69 | GPR84 (0.38) | — | |
| Hydrochloric Acid SCHEMBL21411990 | 0.68 | — | — | |
| SCHEMBL29891752 | 0.67 | PDE5A (0.51) | — | |
| SCHEMBL9151923 | 0.67 | — | — | |
| Thiouracil SCHEMBL2856254 | 0.65 | — | — | |
| Uracil SCHEMBL877869 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
| CN-104884096-B | Composition for treating cancer related to human papillomavirus infection | 银汉斯德生物技术公司 | 2022-05-24 | — | — | CN | disclosed |
| EP-3757213-A1 | COMPOSITION FOR TREATING CANCER ASSOCIATED WITH HPV INFECTION | EnhancedBio Inc. (KR) | 2020-12-30 | — | — | EP | disclosed |
| EP-3178498-B1 | COMPOSITION FOR TREATING CANCER ASSOCIATED WITH HPV INFECTION | ENHANCEDBIO INC (KR) | 2020-11-18 | — | — | EP | disclosed |
| CN-107108685-B | MiR-29 mimetics and uses thereof | 米拉根医疗股份有限公司 | 2020-10-20 | — | — | CN | disclosed |
| EP-3722425-A1 | COMPOSITION FOR TREATING CANCER ASSOCIATED WITH HPV INFECTION | EnhancedBio Inc. (KR) | 2020-10-14 | — | — | EP | disclosed |
| EP-3699278-A1 | COMPOSITION FOR TREATING CANCER ASSOCIATED WITH HPV INFECTION | EnhancedBio Inc. (KR) | 2020-08-26 | — | — | EP | disclosed |
| EP-3699279-A1 | COMPOSITION FOR TREATING CANCER ASSOCIATED WITH HPV INFECTION | EnhancedBio Inc. (KR) | 2020-08-26 | — | — | EP | disclosed |
| US-10221418-B2 | Composition for treating cancer associated with HPV infection | EnhancedBio Inc. (KR) | 2019-03-05 | — | — | US | disclosed |
| WO-2004015117-A2 | TARGETED GENE MODIFICATION BY SINGLE-STRANDED DNA OLIGONUCLEOTIDES | NEDERLANDS KANKER INSTITUUT (NL) | 2004-02-19 | — | — | WO | disclosed |
| CN-1351497-A | Aminopyrimidines as sorbitol dehydrogenase inhibitors | PFIZER PROD INC (US) | 2002-05-29 | — | — | CN | disclosed |
| EP-0058055-B1 | PROCESS FOR PREPARING SUBSTITUTED PYRIMIDINONES AND INTERMEDIATES THEREFOR | SMITHKLINE BECKMAN CORPORATION (US) | 1987-09-23 | — | — | EP | disclosed |
| US-4675406-A | Substituted pyrimidinones | SMITHKLINE BECKMAN CORPORATION (US) | 1987-06-23 | — | — | US | disclosed |
| US-4620001-A | Chemical methods and intermediates for preparing substituted pyrimidinones | SMITHKLINE BECKMAN CORPORATION (US) | 1986-10-28 | — | — | US | disclosed |
| EP-0141973-A2 | Process for preparing substituted pyrimidinones and intermediates therefor | SMITHKLINE BECKMAN CORPORATION (US) | 1985-05-22 | — | — | EP | disclosed |
| US-4477663-A | Intermediates for preparing substituted pyrimidinones | SMITHKLINE BECKMAN CORPORATION (US) | 1984-10-16 | — | — | US | disclosed |
| US-4352933-A | Chemical methods and intermediates for preparing substituted pyrimidinones | SMITHKLINE BECKMAN CORPORATION (US) | 1982-10-05 | — | — | US | disclosed |
| EP-0058055-A2 | Process for preparing substituted pyrimidinones and intermediates therefor | SMITHKLINE BECKMAN CORPORATION (US) | 1982-08-18 | — | — | EP | disclosed |
| US-3975374-A | Process for preparing 2-thiouracil nucleosides | THE UPJOHN COMPANY (US) | 1976-08-17 | — | — | US | disclosed |