Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.39 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.39 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17576252 | 0.76 | KDM4E (0.49) | KMT2AKCNA3HSD17B10HPGDALDH1A1 | |
| SCHEMBL31376342 | 0.71 | PPARG (0.64) | KMT2APPARGPPARAHSD17B10HPGD | |
| SCHEMBL16933413 | 0.71 | PPARG (0.64) | KMT2APPARGPPARAHSD17B10HPGD | |
| SCHEMBL16933412 | 0.71 | PPARG (0.64) | KMT2APPARGPPARAHSD17B10HPGD | |
| SCHEMBL2922977 | 0.71 | PPARG (0.64) | KMT2APPARGPPARAHSD17B10HPGD | |
| SCHEMBL9315719 | 0.70 | KMT2A (0.56) | KMT2APPARGPPARAHSD17B10CYP1A2 | |
| SCHEMBL18379271 | 0.69 | BRPF1 (0.47) | HSD17B10HPGDCA12BRD4BRPF1 | |
| SCHEMBL9385739 | 0.69 | MAPT (0.53) | KMT2AHSD17B10HPGDALDH1A1CA12 | |
| SCHEMBL9643343 | 0.69 | KMT2A (0.68) | KMT2APLA2G2APPARGPPARAHPGD | |
| SCHEMBL6270120 | 0.68 | KMT2A (0.49) | KMT2APPARGPPARAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313947-A | TREATMENT OF BLOOD DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
| US-4216220-A | Platelet aggregation inhibiting 2-oxyindoles, their compositions and method of use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-08-05 | — | — | US | disclosed |
| US-4070470-A | BENCYCLOAMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1978-01-24 | — | — | US | disclosed |