Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478119 | 0.78 | KDM4E (0.61) | MAPTHTTCA12BRD4BRPF1 | |
| SCHEMBL835056 | 0.77 | KDM4E (0.65) | MAPTHTTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL13478643 | 0.77 | BRPF1 (0.50) | MAPTHTTCA12BRD4BRPF1 | |
| SCHEMBL15519805 | 0.77 | BRPF1 (0.50) | MAPTHTTCA12BRD4BRPF1 | |
| SCHEMBL2070484 | 0.77 | BRPF1 (0.50) | MAPTHTTCA12BRD4BRPF1 | |
| SCHEMBL29471261 | 0.77 | BRPF1 (0.50) | MAPTHTTCA12BRD4BRPF1 | |
| SCHEMBL10570214 | 0.77 | KDM4E (0.66) | MAPTKDM4EALDH1A1CYP2C19HTR2C | |
| SCHEMBL23095471 | 0.76 | NPEPPS (0.50) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL20824763 | 0.74 | CA12 (0.47) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL18379271 | 0.74 | BRPF1 (0.47) | MAPTHTTCA12BRD4BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994003425-A2 | CARBOSTYRIL DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIA | SYNTEX (U.S.A.) INC. (US) | 1994-02-17 | — | — | WO | disclosed |