Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287838 | 0.98 | NPC1 (0.41) | HPGDHTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL11288813 | 0.96 | NPC1 (0.43) | HPGDKMT2ANPC1RAB9AATM | |
| Hydrochloric Acid SCHEMBL11291331 | 0.95 | NPC1 (0.42) | HPGDKMT2ANPC1RAB9AATM | |
| Hydrochloric Acid SCHEMBL11276339 | 0.94 | RAB9A (0.39) | HPGDKMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL11287434 | 0.87 | ATM (0.44) | HPGDKMT2ANPC1RAB9AATM | |
| SCHEMBL11289958 | 0.81 | NPC1 (0.44) | HPGDNPC1RAB9APDE4BPDE4D | |
| SCHEMBL11281246 | 0.80 | PDE4A (0.50) | HPGDTDP1L3MBTL1PDE4BPDE4D | |
| SCHEMBL11290594 | 0.79 | ALDH1A1 (0.48) | RAB9AADRB2 | |
| SCHEMBL11284327 | 0.79 | HPGD (0.47) | HPGDKMT2ATDP1ITGB3ITGA2B | |
| SCHEMBL11420372 | 0.79 | PDE4D (0.35) | KMT2ARAB9AADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |