Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.75 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.75 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.75 |
| ▸ | RXRA | P19793 | 1/20 | 0.73 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | CA6 | P23280 | 1/20 | 0.65 |
| ▸ | CA7 | P43166 | 1/20 | 0.65 |
| ▸ | TPMT | P51580 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.65 |
| ▸ | PDE4A | P27815 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1029034 | 1.00 | SMPD1 (0.75) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| Hydrochloric Acid SCHEMBL6586504 | 0.98 | SMPD1 (0.73) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| SCHEMBL11271923 | 0.98 | SMPD1 (0.73) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| SCHEMBL242563 | 0.94 | MRGPRX4 (0.77) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| SCHEMBL11277266 | 0.93 | MRGPRX4 (0.75) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| SCHEMBL29556736 | 0.91 | MRGPRX4 (0.62) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| SCHEMBL1600077 | 0.91 | MRGPRX4 (0.62) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| SCHEMBL4270566 | 0.90 | SMPD1 (0.73) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| SCHEMBL9236564 | 0.90 | SMPD1 (0.73) | SMPD1HDAC1HDAC8HDAC6RXRA | |
| Hydrochloric Acid SCHEMBL10857748 | 0.89 | MRGPRX4 (0.61) | SMPD1HDAC1HDAC8HDAC6RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3947352-A1 | COMPLEMENT MODULATORS AND RELATED METHODS | RA Pharmaceuticals, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |